The new treatment method for sleep associated bruxism by using electrical stimulation

利用电刺激治疗睡眠相关磨牙症的新方法

• 批准号: 05557088
• 负责人: NAKANO Masanori
• 金额: $ 5.63万
• 依托单位: The University of Tokushima, School of Dentistry
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05557088/
• 关键词: Bruxism; Multi telemetor system; Tempolomandibular disorders; Electrical stimulation; Sleep; 顎口腔機能; 顎運動測定

The purpose of this research is to develop a new treatment method for sleep associated bruxism by using electrical stimulation.1. We developed a new polysomnographic system for the measurement of bruxism using the multitelemeter system and the PCM data recorder.2. Sleep associated bruxism was detected by the polysomnograhic system which allows the simultaneous measurements of EMG,jaw movement, respiration, ECG,EOG and EEG.Experimental recordings were done for three nights in each subject. The data revealed that both grinding and clenching type bruxism events existed during sleep and each type of event was associated with the specific change of the sleep stage.4. Electrical stimulation for the treatment of bruxism was triggered by masseter muscle activity. The stimulation device was operated by battery. Appropriate stimulation signal intensity, frequency, time duration were studied, but we still need to improve the device for the fail-safe system.5. The result of this study exhibits the several physiological phenomena associated with bruxism during sleep. When the further studies are done, we will be able to develop the effective and harmless remedy for this sleep associated oral motor dysfunction-BRUXISM.

本研究的目的是开发一种新的电刺激治疗睡眠相关性磨牙症的方法.我们利用多路遥测系统和PCM数据记录器开发了一种新的多导睡眠图测量磨牙症的系统.用多导睡眠图检测仪同时检测EMG、下颌运动、呼吸、ECG、EOG和EEG，对每名受试者进行连续三夜的实验记录。研究结果显示，磨牙和磨牙事件在睡眠中同时存在，且每种类型的磨牙事件都与睡眠阶段的特定变化相关.电刺激治疗磨牙症是由咬肌活动触发的。刺激装置由电池供电。对合适的刺激信号强度、频率、持续时间进行了研究，但仍需对装置进行改进，使系统具有故障安全性.本研究的结果显示了睡眠中与磨牙症相关的几种生理现象。随着研究的深入，我们将有可能开发出治疗这种睡眠相关的口腔运动功能障碍的有效而无害的药物--磨牙症。

项目成果

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Glenn T.Clark: "Co-activation of sternocleidomastoid muscle during maximum clenching" Journal of Dental Research. 72. 1499-1502 (1993)

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西川,啓介: "閉塞型睡眠時無呼吸症候群/-歯科との関連性ならびにUCLAにおける研究と治療の現状について-" 日本歯科評論. 614. 187-198 (1993)

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P.A.Brown: "Sternocleidomastoid muscles inhibition induced by trigeminal stimulation" Journal of Dental Research. 72. 1503-1508 (1993)

P.A.Brown：“三叉神经刺激引起的胸锁乳突肌抑制”《牙科研究杂志》。