微小電流刺激による同種骨骨形成促進化に関する実験的研究

微电流刺激促进同种异体骨形成的实验研究

• 批准号: 06771938
• 负责人: 和田 和郎
• 金额: $ 0.58万
• 依托单位: Ohu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Encouragement of Young Scientists (A)
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-06771938/
• 关键词: 同種骨移植; 微小電流刺激; 病理組織学的変化; CMR

組織学的検索において、通電1日目における電極周囲の組織学的変化は非通電側と特に大きな変化はみられなかった。通電3日目では電極周囲に毛細血管および線維性結合織の増生が、非通電側にくらべ密に認められた。通電5日目は線維性結合織の肥厚、骨芽細胞の増生を認め、既存皮質骨側に新生骨梁が見られたが、非通電側においては骨梁形態をとるも電極周囲に限局していた。通電7日目では新生骨梁が非通電側に比べ多数認められ、内骨膜に沿って骨髄腔全体に成長し、移植骨に破骨細胞の出現を認めた。CMR検索において7日例では、既存皮質骨断端付近に形成された新生骨がX線不透過度の極めて低い梁状構造を呈しており、移植骨は不透過性であった。以上の所見より10μAの直流微小電流刺激は、骨欠損部の初期治癒過程においてinternal remodelingを活発にし、骨形成を促進させた。

On the one hand, there is a demand for information on the course of study, and on the first day, on the first day of the program, there is a special training program for college students. On the 3rd, you can use the information of hair and blood vessels on the 3rd, and the information of the students in the department of health and non-electricity. For 5 days, the results showed that the tissue was hypertrophic, the bone germ cells were damaged, the existing skin bone was born, the new bone was born, and the shape of the bone beam was not connected to the electronic. the morphology of the bone beam was very limited to that of the local government. On the 7th day, the new bone trabeculae were found in most cases, the endoperiosteum was lengthened along the bone cavity, and the broken bone cells were found in the grafts. In 7 cases of CMR occlusion, the broken end of the existing skin bone was closed to the bone, the X line of the new bone was impenetrable, the low bone beam was tight, and the grafted bone was impenetrable. As seen above, 10 μ A DC micro-current stimulation, initial treatment of bone defect, internal remodeling activation and bone formation promotion were performed.