权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

A NEW APPROACH TO THE ORIGIN OF LIFE BY STUDYING CHIRAL POLYMERIZATION OF AMINO ACIDS IRRADIATED BY CIRCULARLY POLARIZED LIGHT

通过研究圆偏振光照射下氨基酸的手性聚合，探索生命起源的新途径

基本信息

批准号：
07409005
负责人：
AMAKAWA Taisaku
金额：
$ 20.22万
依托单位：
KOBE UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1997
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07409005/
关键词：
amino acids chiral polymerization origin of life circularly polarized light synchrotron radiation

项目摘要

(1) Circularly polarized light has been suggested as a main factor that induces homochiral amino acids. We tried to detect an absolute asymetric decomposition of amino acids by introducing helical undulator radiation.(2) We succeeded in preparing dried thin films of amino acids (Alanine, Aspartic, acid and Phenylalanine) of which thickness was determined with accuracy.(3) We obtained absorption spectra and CD spectra of ultra violet radiation light (175-250nm) on the dried films or aqueous amino acids.(4) We could not, however, detect a significant difference of asymmetrical decomposition between L- and D-type amino acid under clockwise or counterclockwise polarized lights at 205 nm, where CD-absorption difference is the highest.(5) The similar results as above were obtained for acidic solution of amino acids.(6) Absolute values of optical absorption coefficient of amino acids were determined.(7) The results of organic chemistry experiment independently curried out showed that the homochiral oligo peptides (e.g.L-L-L-L) were more stable to hydrolysis at 100ﾟC than the heterochiral oligo peptide (e.g.L-L-L-D).(8) These findings described here would give a valuable clue to understand the chirality formation and chemical evolution of life materials.

(1)圆偏振光被认为是产生同手性氨基酸的主要因素。我们试图通过引入螺旋波动辐射来检测氨基酸的绝对不对称分解。(2)成功制备了氨基酸（丙氨酸、天冬氨酸、氨基酸和苯丙氨酸）的干燥薄膜，并准确测定了薄膜的厚度。(3)得到了干燥膜或氨基酸水溶液的吸收光谱和CD光谱（175 ~ 250nm）。(4)在205 nm处，顺时针偏振光和逆时针偏振光下，L型和d型氨基酸的不对称分解没有显著差异，此时cd吸收差异最大。(5)氨基酸酸性溶液与上述结果相似。(6)测定了氨基酸的光学吸收系数绝对值。(7)独立进行的有机化学实验结果表明，同手性低聚肽（如l - l - l - l - l）比异手性低聚肽（如l - l - l - d）在100℃下更稳定地水解。(8)这些发现将为理解生命物质的手性形成和化学演化提供有价值的线索。