Living down to expectations: generic medicines and the nocebo effect

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This project aims to generate new knowledge of how the awareness of taking a generic medicine can lead to increased nocebo effects (side effects caused by negative expectations). The project is expected to deepen scientific understanding of how generics can trigger nocebo effects by using an innovative experimental approach to tease out contributing key features, explore the role of conscious and nonconscious negative expectations, and test novel strategies to reduce these nocebo effects. Expected outcomes of this project include theory development and enhanced understanding of nocebo effect causes and mechanisms. This should provide significant benefits, including potential strategies for mitigating nocebo effects of generic medicines.