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Analytical system of free moving-exercise for animal on an experimental1 basis.

基于实验的动物自由运动分析系统。

基本信息

批准号：
07557217
负责人：
KIMURA Mieko
金额：
$ 0.77万
依托单位：
KYOTO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1996
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07557217/
关键词：
free moving exercise analytical system of behavior animal nutrition magnesium

项目摘要

Recently, effects of lack of exercise and westernizing of food habits on health status based urbanizing of daily life are focused in Japan. On the other hand, health status of students belonged to an athletic club under unbalanced nutritional in take are also picked up. A free moving system was designed for exercise of rats, that is 4 case (80 m * 20 cm * 25 cm) were arranged lengthways through three pipes (10 cm ID), and drinking water on upstairs and diets were set up under ground. In the free moving system (Ex+) or the conventional system (Ex-), rats fed low magnesium (Mg1/3) diet or normal diet (Mg+), (total 4 groups ; 1)Ex-Mg+, 2)Ex+Mg+, 3)Ex-Mg-, 4)Ex+Mg-) were kept for 40 days. Muscle weight decreased in rats of group 4 compared to group 1.After sampling, biochemical items in plasma, and total lipid, lipid peroxide, protein and superoxide dismutase (total-SOD,Mn-SOD) in liver were measured. In plasma of group 4, ALB,AMY,LDH,CPK,UA & CRE were significantly low compared to that of group 1 and PL,T-CHO,ALB,ALP & UA in group 4 were low compared to that of group2.In plasma of group 3, UA was significantly low compared to that of group 1 and PL,ALB,ALP,CHE & UA were low compared to group 2.In lipid peroxide of liver of groups 1 & 2 was significantly high compared to that of other groups. These results suggested that health status under low Mg nutrition would be fallen down by exercise.

最近，缺乏运动和饮食习惯西化对基于日常生活城市化的健康状况的影响在日本受到关注。另一方面，运动俱乐部学生在膳食营养不均衡的情况下，其健康状况也有所改善。设计了一个自由活动的大鼠运动系统，即4个箱子（80 m × 20 cm × 25 cm）纵向排列，通过3个管道（10 cm ID），楼上饮水，地下设饲料。在自由活动系统（Ex+）或常规系统（Ex-）中，饲养低镁（Mg 1/3）饮食或正常饮食（Mg+）的大鼠（共4组; 1）Ex-Mg+，2）Ex+Mg+，3）Ex-Mg-，4）Ex+Mg-）40天。各组大鼠肌肉重量均较对照组减轻。采血后测定血浆生化指标、肝脏总脂质、过氧化脂质、蛋白质和超氧化物歧化酶（total-SOD、Mn-SOD）。第4组血浆ALB、AMY、LDH、CPK、UA、CRE显著低于第1组，PL、T-CHO、ALB、ALP、UA显著低于第2组;第3组血浆UA显著低于第1组，PL、ALB、ALP、CHE和UA较2组低，肝脏脂质过氧化物含量1、2组明显高于其他组。提示低镁营养状态下的健康状况会因运动而下降。