A STUDY OF MODELING PATHOLOGICAL VOCAL CORDS WITH APPLICATION TO THE DIAGNOSIS OF LARYNGEAL DISEASES THROUGH THE ACOUSTIC ANALYSIS OF HOARSE VOICE

病理声带建模研究及其在嘶哑声声学分析中诊断喉部疾病的应用

• 批准号: 07805036
• 负责人: KOIZUMI Takuya
• 金额: $ 1.41万
• 依托单位: FUKUI UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07805036/
• 关键词: hoarse voice; laryngeal disease; vocal cord vibration; glottal source model; acoustic analysis; estimation of vocal cord features; analysis by synthesis

(1) We have developed several novel models of pathological vocal cords including vocal cords with nodules or a single polyp using the acoustic analysis of hoarse voices and video pictures of pathological vocal cords with relevant diagnoses made by otolaryngologists.(2) We have investigated relations between physical conditions of those models and acoustic features of hoarse voice synthesized with the models.(3) We have found some acoustic features of hoarse voice, in terms of which it is possible to effectively represent hoarse voices. They are found to be useful for the diagnosis and estimation of some physical features of pathological vocal cords. This finding has enabled us to develop a new noninvasive procedure for estimating vocal cord nodule or polyp features such as the mass and stiffness of nodule or polyp through the acoustic analysis of hoarse voice.Findings from the study are as follows :[1] A novel model of pathological vocal cords is able to simulate the subtle movement of the vocal cords in the presence of aspiration noise in the glottis and is able to produce synthetic voices which mimic patients' voices.[2] By the newly developed procedure it is possible to estimate dimensions of vocal cord nodules only through hoarse voice analysis.[3] Estimated noise power spectrum and waveform information such as amplitudes and phases of harmonic frequency components of hoarse voice are useful for estimating vocal cord nodule features.

(1)我们利用耳鼻喉科医生对声带沙哑的声学分析和病理声带的相关诊断的视频图像，建立了几种新的病理声带模型，包括结节或单一息肉的声带。(2)我们研究了这些模型的物理条件与模型合成的沙哑声音声学特征之间的关系。(3)我们发现了一些沙哑声音的声学特征，根据这些特征可以有效地表示沙哑声音。它们被发现对病理声带的某些物理特征的诊断和估计是有用的。这一发现使我们能够开发一种新的无创方法，通过对沙哑声音的声学分析来估计声带结节或息肉的质量和硬度等特征。本研究的结果如下：一种新的病理声带模型能够模拟声门中存在吸入噪声时声带的细微运动，并能够产生模仿患者声音的合成声音通过新开发的方法，仅通过沙哑的声音分析就可以估计声带结节的大小估计的噪声功率谱和沙哑声音谐波频率分量的幅值和相位等波形信息有助于估计声带结节的特征。

项目成果

Takuya Koizumi: "An Analysis-by-Synthesis Approach to the Estimation of Vocal Cord Nodule Features" Proceedings of 13th International Congress of Phonetic Sciences(ICPhS 95). 2. 254-257 (1995)

Takuy​​a Koizumi：“声带小结特征估计的分析综合方法”第 13 届国际语音科学大会论文集 (ICPhS 95)。

谷口秀次: "Analysis by Synthesis法による声帯結節の特徴推定" 日本音響学会誌. 52. 770-778 (1996)

Hidetsugu Taniguchi：“使用综合分析法估计声带小节的特征”，日本声学学会杂志 52. 770-778 (1996)。

Shuji Taniguchi, Takuya Koizumi, and Akemi Imazawa: "An AbS Approach to the Estimation of Vocal Cord Nodule Features" The Journal of the Acoustical Society of Japan. 52. 770-778 (1996)

Shuji Taniguchi、Takuy​​a Koizumi 和 Akemi Imazawa：“声带小结特征估计的 AbS 方法”日本声学学会杂志。

Takuya Koizumi: "An Analysis-by-Synthesis Approach to the Estimation of Vocal Cord Nodule Features" Proceedings of 13th International Congress of Phonetic Sciences (ICPhS 95). 2. 254-257 (1995)

Takuy​​a Koizumi：“声带小结特征估计的综合分析方法”第 13 届国际语音科学大会 (ICPhS 95) 会议记录。

Takuya Koizumi, Shuji Taniguchi, Mikio Mori, and Akemi Imazawa: "An Analysis-by-Synthesis Approach to the Estimation of Vocal Cord Nodule Features" Proceedings of 13th International Congress of Phonetic Sciences (ICPhS 95). 2. 254-257 (1995)

Takuy​​a Koizumi、Shuji Taniguchi、Mikio Mori 和 Akemi Imazawa：“声带小结特征估计的综合分析方法”第 13 届国际语音科学大会 (ICPhS 95) 会议记录。