A study on the visco-elastic properties of the extraocular muscles

眼外肌粘弹性特性的研究

• 批准号: 07671944
• 负责人: KIMURA Hisashi
• 金额: $ 0.9万
• 依托单位: KAWASAKI MEDICAL SCHOOL
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07671944/
• 关键词: extraocular muscle; contraction; visco-elasticity

We examined the visco-elastic properties of the slow and fast fibers consisting the superior rectus muscle (SR) and retractor bulbi muscle (RB) of rabbits. Eighteen to nineteen percent of whole muscle tension was produced by slow fibers in SR and one to five percent by those in RB.After long continuous contraction, fatigue-resistant fibers left residual tension in SR,but the tension was almost entirely absent in RB.The frequency response method was used to evaluate dynamic visco-elasticity. The muscle was stretched sinusoidally, with an amplitude of 1 mm at 20 Hz in Lmax. The tension amplitude to sine wave vibrations during tetanus (P) and resting (P_0) were then examined. The dynamic stiffness ratio (P/P_0) was higher in SR (3.1) than in RB (2.0). It was suggested that the visco-elasticity of the activated cross bridges at myosin and actin filaments are greater in slow fibers than in fast fibers.We concluded that these properties support the hypothesis of the slow fibers to stabilize the eye balls.

我们检查了由兔子的上直肌（SR）和牵开球肌（RB）组成的慢纤维和快纤维的粘弹性特性。 SR中18%至19%的整个肌肉张力由慢纤维产生，RB中的慢纤维产生1%至5%。在长时间连续收缩后，抗疲劳纤维在SR中留下残余张力，而RB中几乎完全不存在张力。采用频率响应法来评估动态粘弹性。肌肉以正弦曲线拉伸，Lmax 为 20 Hz，振幅为 1 mm。然后检查破伤风 (P) 和静息 (P_0) 期间正弦波振动的张力幅度。 SR (3.1) 中的动态刚度比 (P/P_0) 高于 RB (2.0)。有人认为，慢纤维中肌球蛋白和肌动蛋白丝上激活的跨桥的粘弹性大于快纤维中的粘弹性。我们得出的结论是，这些特性支持慢纤维稳定眼球的假设。

项目成果

Hiraki Y,Kimura H,Tabuchi A: "Studies on kinetic visco-elasticity of slow muscle fibers" J.Jpn. Ophthalmol. Soc.101. 3-11 (1997)

Hiraki Y，Kimura H，Tabuchi A：“慢肌纤维的动力粘弹性研究”J.Jpn。

木村 久: "眼球運動における外眼筋slow fiberの働き" 日本眼科学会雑誌. 99. 210 (1995)

Hisashi Kimura：“眼球运动中眼外肌慢纤维的功能”日本眼科学会杂志 99. 210 (1995)。

木村久: "外眼筋slow fiberの収縮特性について" 神経眼科. 13・増補. 31 (1995)

Hisashi Kimura：“眼外肌慢纤维的收缩特性”，《神经眼科》13，增刊 31（1995）。

木村久: "眼球運動における外眼筋slow fiberの働き" 日本眼科学会雑誌. 99・臨増. 210 (1995)

Hisashi Kimura：“眼球运动中眼外肌慢纤维的功能”，日本眼科学会杂志 99，Rinzo。

Kimura H,Hiraki Y,Tabuchi A: "Roles of the slow fibers on the eye movements" J.Jpn. Ophthalmol. Soc.99. 210 (1995)

Kimura H、Hiraki Y、Tabuchi A：“慢纤维对眼球运动的作用”J.Jpn。