Neuronal activity and attention in the primary visual cortex

初级视觉皮层的神经元活动和注意力

• 批准号: 08458268
• 负责人: SATO Hiromichi
• 金额: $ 4.42万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08458268/
• 关键词: primary visual cortex; stimulus specificity; stimulus-cortex dependency; cat; functional domain; horizontal connection; 視覚的注意; 図-地分化; 受容野特性の修飾; 文脈依存性

To study mechanisms for an integration of stimulus information distributing wide area in the visual field, we examined modulatory effects of visual responses of neurons by grating stimuli presented outside of receptive field in the primary visual cortex of anesthetized cats. Responses to the optimally oriented grating patch in the receptive field were suppressed by surrounding stimulus particularly in complex cells of the superficial layer. Effectiveness of surrounding stimulus was dependent on relationship between the cell's preferred spatial frequency (SF) and the SF of surrounding grating. Among the 21 cells which exhibited significant suppression with a presence of surrounding stimulus, the most effective SF of surrounding stimulus for the suppressive modulation was same as that of the optimal SF for the receptive field stimulus in 12 cells and different in 6 cells. In remaining 3 cells, SF dependency of the response modulation by SF was not observed. Our results suggest that neural connection among SF domains sharing similar SF preference is one of the basis of the contextual modulation of responses in the visual cortex.

为研究刺激信息在视野中广泛分布的整合机制，我们在麻醉猫初级视皮层观察了感受野外光栅刺激对神经元视觉反应的调制作用。在感受野中的最佳取向的光栅补丁的反应被抑制周围的刺激，特别是在复杂的细胞的表层。环境刺激的有效性取决于细胞偏好的空间频率（SF）与环境光栅的SF之间的关系。在21个对周围刺激有明显抑制作用的细胞中，有12个细胞的周围刺激对抑制性调制的最有效SF与感受野刺激的最佳SF相同，有6个细胞不同。在剩余的3个细胞中，没有观察到SF依赖性的响应调制SF。我们的研究结果表明，SF域共享相似的SF偏好之间的神经连接是在视觉皮层的反应的上下文调制的基础之一。

项目成果

Yoshimura, Y., Sato, H., Imamura, K. and Watanabe, Y.: "Properties of horizontal and vertical inputs to pyramidal cells in the superficial layers of the cat visual cortex"Journal of Neuroscience. 20(5)(in press). (2000)

Yoshimura, Y.、Sato, H.、Imamura, K. 和 Watanabe, Y.：“猫视觉皮层表层锥体细胞的水平和垂直输入的特性”神经科学杂志。

佐藤宏道 他: "一次視覚野における特徴抽出のメカニズムと刺激文脈依存性"脳の科学. 21(5). 519-525 (1999)

Hiromichi Sato 等人：“初级视觉皮层特征提取和刺激上下文依赖性的机制”《脑科学》21(5) (1999)。

Sato, H., Hata, Y. and Tsumoto, T.: "Effects of blocking non-NMDA receptors on visual responses in the cat visual cortex"Neuroscience. 94. 7697-03 (1999)

Sato, H.、Hata, Y. 和 Tsumoto, T.：“阻断非 NMDA 受体对猫视觉皮层视觉反应的影响”神经科学。

Shimegi, S., Ichikawa, T., Akasaki, T. and Sato, H.: "Temporal characteristics of response integration evoked by multiple whisker stimulations in the barrel cortex of rats"Journal of Neuroscience. 19. 10164-10175 (1999)

Shimegi, S.、Ichikawa, T.、Akasaki, T. 和 Sato, H.：“大鼠桶状皮层多次胡须刺激引起的反应整合的时间特征”神经科学杂志。

Sato,H.et al.: "Effects of blocking non-NMDA receptors on visual responses in the cat visual cortex."Neuroscience. 94. 697-703 (1999)

Sato, H.等人：“阻断非 NMDA 受体对猫视觉皮层视觉反应的影响。”神经科学。