3T MR Imager for small animals

适用于小动物的 3T MR 成像仪

• 批准号: 528336730
• 金额: --
• 依托单位: Martin-Luther-Universität Halle-Wittenberg
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2023
• 资助国家: 德国
• 起止时间: 2022-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/528336730?language=en
• 关键词: 3T; MR; Imager; small; animals

The Martin Luther University Halle Wittenberg (MLU) applies for the procurement of a preclinical MRI device with the field strength of 3 Tesla. It is planned that the device will become part of the Halle MR Imaging Core Facility (HMRICF). The primary users will be research groups from the Institute of Pharmacy and the School of Medicine. One focus of use will be non-invasive MR imaging for characterization of drug delivery systems, especially biodegradable implants and nanoscale delivery systems. Another focus for the use of the MRI device is for imaging pharmacological-oncological issues for several research groups in medicine and pharmacy. As part of the Core Facility, the MRI device is available to other Martin Luther University users from the natural sciences and medicine (first priority) as well as non-university users (second priority). The prioritization of the applications as well as the technical support is carried out by the Core Facility HMRICF. Examples of intended uses are imaging methods for vascular anomalies and their therapy, for cardiological questions (preclinical models of myocardial infarction), for the measurement of fat distributions, for the imaging of age-related changes. It is planned to intensify and expand existing co-operations of different working groups of the natural science faculties with working groups of medicine. One focus of the interfaculty and interdisciplinary cooperation is the development of innovative drug delivery systems for local release. For example, the device will be used for imaging of biodegradable cochlear implants in guinea pigs. Furthermore, the device will be used for advanced training of young scientists. It is planned to use the device for the education of students in the course of studies of medical physics, furthermore master theses, diploma theses and doctorates are planned, in which preclinical imaging by MRI will be an essential part.

马丁路德大学Halle Wittenberg（MLU）申请采购场强为3特斯拉的临床前MRI器械。计划该器械将成为Halle MR成像核心机构（HMRICF）的一部分。主要用户将是来自药学研究所和医学院的研究小组。使用的一个重点将是非侵入性磁共振成像表征的药物输送系统，特别是可生物降解的植入物和纳米级输送系统。使用MRI设备的另一个重点是为医学和药学的几个研究小组成像药理学-肿瘤学问题。作为核心设施的一部分，MRI设备可供其他马丁路德大学自然科学和医学用户（第一优先）以及非大学用户（第二优先）使用。应用程序的优先次序以及技术支持由核心设施HMRICF进行。预期用途的示例包括血管异常及其治疗的成像方法、心脏病学问题（心肌梗死的临床前模型）、脂肪分布测量、年龄相关变化的成像。计划加强和扩大自然科学系不同工作组与医学工作组之间的现有合作。学院间和跨学科合作的一个重点是开发用于本地释放的创新药物递送系统。例如，该设备将用于豚鼠可生物降解人工耳蜗植入物的成像。此外，该设备将用于年轻科学家的高级培训。计划将该设备用于医学物理学研究过程中的学生教育，此外还计划撰写硕士论文、文凭论文和博士学位论文，其中MRI临床前成像将是重要组成部分。