VALUATION OF INTERACTION BETWEEN ORGANIC-INORGANIC HYBRID PARTILCES AND APPLICATION TO CHEMICAL LIBRAR

有机-无机杂化颗粒之间相互作用的评估及其在化学图书馆中的应用

• 批准号: 10640561
• 负责人: YOSHINAGA Kohji
• 金额: $ 2.24万
• 依托单位: KYUSHU INSTITUTE OF TECHNOLOGY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10640561/
• 关键词: Ultrafine particles; Surface modification; Aggregation-dispersion; Inter-particle interaction; Chemical library; Colloid particles; Polymer modification; Hybrid particles; 粒子間相互作用

(1) Surface modification of monodisperse colloidal silica with polymer silane coupling agent Efficient adsorption of poly(maleic anhydride-styrene)(P(MA-ST))-silane coupling on ultrafine colloidal silica particles led to effective reaction of trimethyl silyl group with surface silanol.(2) The reaction of P(MA-ST)-modified silica particles with amino-terminated polymer resulted in the preparation of the composite particles dispersible in low polar solvents. The surface polymer chains on P(MA-ST)-modified silica attached to the surface via 4 siloxane bondings on solid state ィイD129ィエD1Si and ィイD113ィエD1C-NMR spectra.(3) The composite particles prepared with the two-step modification dispersed in good solvent for the secondary polymer via excluded volume effect, and in poor solvent the aggregation-dispersion was controlled through a delicate balance between the attraction of insoluble polymer chains and electrostatic repulsion among particles. Monodisperse composite particles formed colloid crystal in a good solvent for the modified polymer.(4) Weak interactions between the surface polymer chains and the substrate molecules in suspension were evaluated by the spin-spin relaxation time (TィイD22ィエD2) on a NMR technique. It is suggested that the values are applicable to the evaluation of chemical library using the present composite particles.

(1)高分子硅烷偶联剂对单分散硅溶胶的表面改性聚（马来酸酐-苯乙烯）（P（MA-ST））-硅烷偶联剂在硅溶胶微粒表面的有效吸附导致了三甲基硅基与表面硅烷醇的有效反应。(2)P（MA-ST）改性的二氧化硅粒子与端氨基聚合物的反应导致在低极性溶剂中分散的复合粒子的制备。P（MA-ST）改性的二氧化硅表面聚合物链通过4个硅氧烷键连接到表面上，在固态的聚二甲基硅氧烷D129聚二甲基硅氧烷D1 Si和聚二甲基硅氧烷D113聚二甲基硅氧烷D1C-NMR谱上。(3)两步改性法制备的复合粒子在良溶剂中通过排斥体积效应分散于二次聚合物中，在不良溶剂中通过不溶性聚合物链的吸引力和粒子间的静电排斥力之间的微妙平衡控制聚集-分散。单分散复合粒子在改性聚合物的良溶剂中形成胶体晶体。(4)通过NMR技术上的自旋-自旋弛豫时间（T_（22））来评估悬浮液中的表面聚合物链和基底分子之间的弱相互作用。建议这些值适用于使用本复合颗粒的化学库的评价。

项目成果

K.Yoshinaga, T.Kobayashi, H.Karakawa: "Preparation of Polymer electrolyte-Modified Colloidal Silica and controlling of Surface zeta-Potential"Kobunshi Ronbunshu. in press.

K.Yoshinaga、T.Kobayashi、H.Karakawa：“聚合物电解质改性胶体二氧化硅的制备及其表面zeta电位的控制”Kobunshi Ronbunshu。

吉永耕二,小林恒定,辛川弘行: "単分散な高分子電解質修飾コロイダルシリカの調製と表面ゼータ電位の制御"高分子論文集. (印刷中).

Koji Yoshinaga、Tsunesada Kobayashi、Hiroyuki Karakawa：“单分散聚电解质改性胶体二氧化硅的制备和表面 zeta 电位的控制”，聚合物杂志（正在出版）。

K.Yoshinaga, F.Nakashima and T.Nishi: "Polymer Modification of Colloidal Particles by Spontaneous Polymerization of Surface Active Monomers"Colloid and Polymer Science. 277. 136-144 (1999)

K.Yoshinaga、F.Nakashima 和 T.Nishi：“通过表面活性单体的自发聚合对胶体颗粒进行聚合物改性”胶体与聚合物科学。

K.Yoshinaga, I.Toyofuku, K.Yamashita, H.Kanehara, and K.Ohkubo: "Photoinduced Electron Transfer Catalysis of Titania Particles Modified with a Ru(2,2'-bipyridyl)ィイD23ィエD2 ィイD12+ィエD1-Grafted Polymer by Visible Light"Colloid and Polymer Science. in press.

K. Yoshinaga、I. Toyofuku、K. Yamashita、H. Kanehara 和 K. Ohkubo：“可见光下 Ru(2,2-联吡啶)D23D2D12+ D1 接枝聚合物改性二氧化钛颗粒的光致电子转移催化”胶体和聚合物科学正在出版。

吉永耕二、小林恒是、 川弘行: "単分散な高分子電解質-修飾コロイダルシリカの調製と表面ゼータ電位の制御"高分子論文集. (印刷中).

Koji Yoshinaga、Tsuneze Kobayashi、Hiroyuki Kawa：“单分散聚电解质改性胶体二氧化硅的制备和表面 zeta 电位的控制”《聚合物研究杂志》（正在出版）。