Functional Importance of Mutual Isthmo-Tectal Projection in Visually Guided Behavior in the Frog

峡部-顶盖相互投射在青蛙视觉引导行为中的功能重要性

• 批准号: 10640669
• 负责人: MATSUMOTO Nobuyoshi
• 金额: $ 1.34万
• 依托单位: KYUSHU INSTITUTE OF TECHNOLOGY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10640669/
• 关键词: Nucleus Isthmi; Optiac Tectum; frog; Current Source Density Analysis

Nucleus lsthmi receives only input from ipsilateral optic tectum, and it project back to ipsilateral and contralateral optic tectum. This research was carried out to elucidate the functional importance of isthmo-tectal projection.Nucleus Isthmi was electrically stimulated and recorded field potentials from ipsi-and contralateral optict tectum. Current source density analysis was applied to the field potential and depth profiles of the sink and the source were calculated. The following results were obtained.Contralateral Isthmo-tectal ProjectionThere are two sinks with short latency. One fiber group at layer 8 contact monosynaptically to the layer 6 neurons. The other fiber group at superficial tactal layer make monosynaptic contacts to the neurons in layer 8. Existence of the third sink with long latency suggests that neurons in layer 6 receives polysynaptic input from Nucleus Isthmi.Ipsilateral Isthmo-tectal ProjectionThe sink with short latency indicates that neurons in layer 6 receives monosynaptic inputs in layer 8. The other sink with long latency indicates that neurons in layer 6 which projects dendrite to layer 9 receives polysynaptic inputs.

Lsthmi核只接受同侧视顶盖的输入，并投射回同侧和对侧视顶盖。为了阐明峡部顶盖投射的功能重要性，对峡部核进行了电刺激，并记录了同侧和对侧视顶盖的场电位。将电流源密度分析应用于场势，计算了汇和源的深度分布。结果如下：1.对侧峡部顶盖投射有两个潜伏期短的脑池。第8层的一个纤维组与第6层神经元单突触接触。第三个汇区潜伏期较长，提示第6层神经元接受来自峡部核团的多突触输入。同侧峡部顶盖投射，潜伏期短的汇区表示第6层神经元接受第8层神经元的单突触输入，另一个汇区潜伏期较长，表明第6层投射树突至第9层的神经元接受多突触输入。

项目成果

Nakagawa H.Matsumoto N.: "Carrent sourcedensity analysis of ON/OFF channels in the frog optictectum"Progress in Nearobiology. 61・1. 1-44 (2000)

Nakakawa H.Matsumoto N.：“青蛙视顶盖开/关通道的电流源密度分析”近生物学进展61・1（2000）。

Nakagawa, H., Matsumoto, N. et.al.: "Quantitative study of the frog escape behavior to an appraching object"Zoological Science 16 Supplement. 16. 111-111 (1999)

Nakakawa, H.、Matsumoto, N. 等人：“青蛙逃避接近物体行为的定量研究”《动物学科学》第 16 期增刊。

Nakagawa H. and Matsumoto N.: "Current source density analysis of ON/OFF channels in the frog optic tectum"Progress in Neurobiology. 61, No.1. 1-44 (2000)

Nakakawa H. 和 Matsumoto N.：“青蛙视顶盖开/关通道的电流源密度分析”神经生物学进展。

Hoshino N.,Nakagawa H.,Matsumoto N.: "Carrent sourcedensity analysis of the isthmotecfal projection in the frog"Abstracts of 28th Annual Meeting Society for Nearoscience. 2. 1364-1364 (1999)

星野 N.，中川 H.，松本 N.：“青蛙峡部投影的电流源密度分析”第 28 届近科学会年会摘要。

Nakagawa, H., Matsumoto, N.: "Current source density analysis of on/off channel in the frog optic tectum"Progress in Neurobiology. 61-1. 1-44 (2000)

Nakakawa, H.，Matsumoto, N.：“青蛙视顶盖开/关通道的电流源密度分析”神经生物学进展。