Host Selection of Anti-tumor Basidiomycetes meshimakobu (Phellinus linteus) for yamaguwa (Morus bombycis).

山口是众所周知的最耐用的木材之一腐烂在日本。抗肿瘤蘑菇，meshimakobu是典型的发现在这个山口木材。本文试图阐明松天牛选择山口木为寄主的原因，山口木对松天牛的菌丝生长有促进作用，而古木和科那拉木对松天牛的菌丝生长无促进作用。在山口组中，甘露、川原和香菇的生长受到抑制。结果表明，山口组的热水提取物中含有对木腐菌的促进作用，甲醇提取物中含有对其他木腐菌的抑制作用，山口组甲醇提取物中的酚类组分对木腐菌的抑制作用强于木腐菌。氧化白藜芦醇被推测为山口组甲醇提取物的酚级分的主要抗真菌因子。但是，即使在培养基中添加氧化白藜芦醇，Meshimakobu也很弱，很容易被其他木材腐烂真菌击败。从这些结果来看，似乎Meshimakobu只能在山口勉强存活，因为抗真菌因子氧化白藜芦醇显著阻止了其他强大的木材腐烂真菌的生长。

Yamaguwa is well known as one of the most durable wood for decay in Japan. Anti-tumor mushroom, meshimakobu is found typically in this yamaguwa wood. We attempted to clear the reason why mesimakobu selects yamaguwa as a host wood.The mycerial growth of mesimakobu in yamaguwa wood was promoted more than kunugi and konara wood. In the case of mannentake, kawaratake and shiitake, their growth were depressed in yamaguwa wood. It was found that a hot water extracts of yamaguwa contained a promoter for meshimakobu and methanol extracts contained inhibitors for other wood rotting fungi.The phenol fraction of methanol extracts of yamaguwa showed greater antifungal activities for wood rotting fungi, other than meshimakobu. Oxyresveratrol was presumed as a main antifungal factor in a phenol fraction of methanol extracts of yamaguwa. Meshimakobu was however very weak and easily defeated by other wood rotting fungi even when oxyresveratrol was added in a culture medium.From these results, it seems that meshimakobu could be barely survived only in yamaguwa because antifungal factor, oxyresveratrol prevented significantly the growth of other strong wood rotting fungi.