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The new trial Of guidelines for operative indications of VUR

VUR手术指征指南新试验

基本信息

批准号：
10670773
负责人：
MENO Takayo
金额：
$ 1.22万
依托单位：
Kurume Universuty
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 1999
项目状态：
已结题

项目摘要

Reflux nephropathy (RN) is an important disease caused end-stage renal failure in not only children but adults. urinary tract infection and intrarenal reflux (IRR) are considered as facts of RN, and vesicoureteral reflux participates RN.In this study we detected IRR using RI-VCG, compared the international grades of VUR in 23 patients of VUR. And we examined intravenous pyelography, echography, CT scan, DMSA for finding RN. We recognized RN 1 of 4 in grade I 4 of 6 in grade II 7 of 7 in III grade 4 of 4 in grade IV 1 of 2 in grade V.We performed the method for diagnosis of vesicoureteral reflux (VUR) by using (CFD) imaging system. It can display urine flow as slow as 1.4mm/sec. We investigated the urine flow of reflux from bladder or ureter to ureter or renal pelvis.We will investigate the relationships with VUR, IRR and RN. Furthermore we will examine the urodynamics of urine in renal pelvis. They will be useful to prevent the onset of RN and end-stage renal failure.

反流性肾病（RN）是一种重要的疾病引起的终末期肾功能衰竭，不仅在儿童，但成人。本研究应用RI-VCG检测了23例VUR患者的IRR，并与国际上VUR分级进行了比较。同时行静脉肾盂造影、超声心动图、CT扫描、DMSA检查。I级4例中RN 1例，II级6例中RN 4例，III级7例中RN 7例，IV级4例中RN 4例，V级2例中RN 1例。它可以显示尿流慢至1.4毫米/秒。本研究探讨膀胱或输尿管返流至输尿管或肾盂的尿流量，以及返流与VUR、IRR、RN的关系。此外，我们将检查肾盂尿液的尿动力学。它们将有助于预防RN和终末期肾功能衰竭的发生。