Research on the refraction-enhanced imaging using synchrotron radiation

在这项研究中，X射线成像进行了测试，使用平行的X射线束从波纹或光源的SPring-8。用X射线图像探测器在8和28.8keV的X射线能量下测量投影图像，该X射线图像探测器放置在离样品下游5-5.6m处。通过射线追踪模拟，得到了一个测试样品的透射图像，与实验结果吻合较好。强度分布可以通过X射线的折射来解释。透射光束的检测也是用狭缝准直的细X射线束来测量的。X射线穿过样品的偏转角大约是生物标本软组织的几个显微观察值。计算结果与基于几何光学的样品计算结果也吻合较好。该技术适用于生物标本软组织的观察。本文介绍了对裸鼠肺的成像结果，并讨论了接触成像（吸收对比）与折射对比成像的区别，这是一种很有前途的低剂量人体肺诊断新技术。

In this study, X-ray imaging was tested using parallel X-ray beam from undulateor light source of the SPring-8. Projection images were measured at X-ray energies of 8 and 28.8 keV with X-ray image detector that is placed atr 5-5.6m downstream from specimen. Transmission image of a test sample shows good agrrement with ray-trace simulation. The intensity profile can be explained by refraction of X-rays. Detection of Transmitted beam is also measured by using fine X-0ray beam collimated by a slit. The deflection angel of X-rays through the sample is around a few microobservation of soft tissues of biological specimen. The results also well agrees with sample calculation based on geometrical optics. This technique is applied to observation of soft tissues of biological specimen. The result for lung image of nude mouse is preseted, and difference between contact image (absorption-contrast) and refraction contrast image is discussed.This is a promising new technique for the diagnosis in the human lung with a low dose.