Research on the refraction-enhanced imaging using synchrotron radiation

在这项研究中，使用来自SPring-8的波动光源的平行x射线束进行x射线成像测试。投影图像在x射线能量为8和28.8 keV时测量，x射线图像探测器放置在离样品下游5-5.6m处。测试样品的透射图像与射线追踪模拟结果吻合较好。强度分布可以用x射线的折射来解释。透射光束的探测也可以用细x射线束经狭缝准直来测量。x射线通过样品的偏转角在几个生物标本软组织显微观察的范围内。结果与基于几何光学的实例计算结果吻合较好。该技术适用于生物标本软组织的观察。介绍了裸鼠肺部图像的成像结果，并讨论了接触图像（吸收对比）与折射对比图像的区别。这是一种很有前途的低剂量人体肺部诊断新技术。

In this study, X-ray imaging was tested using parallel X-ray beam from undulateor light source of the SPring-8. Projection images were measured at X-ray energies of 8 and 28.8 keV with X-ray image detector that is placed atr 5-5.6m downstream from specimen. Transmission image of a test sample shows good agrrement with ray-trace simulation. The intensity profile can be explained by refraction of X-rays. Detection of Transmitted beam is also measured by using fine X-0ray beam collimated by a slit. The deflection angel of X-rays through the sample is around a few microobservation of soft tissues of biological specimen. The results also well agrees with sample calculation based on geometrical optics. This technique is applied to observation of soft tissues of biological specimen. The result for lung image of nude mouse is preseted, and difference between contact image (absorption-contrast) and refraction contrast image is discussed.This is a promising new technique for the diagnosis in the human lung with a low dose.