Age-related changes of swallowing function

吞咽功能与年龄相关的变化

• 批准号: 10671596
• 负责人: HYODO Masamitsu
• 金额: $ 2.05万
• 依托单位: Ehime University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671596/
• 关键词: aging; swallowing disturbance; video fluorography; pharyngeal manometer; pharyngeal clearance; aspiration; 咽頭食道透視; 嚥下圧伝搬障害; ATPase染色; 神経筋接合部; 筋線維萎縮; 嚥下圧; 咽喉頭異常感症; 咽喉食道透視検査; 筋電図検査

Swallowing function with aging was evaluated by videofluorography and manometric study.1. VideofluorographySubjects consisted of 113 persons who presented Ehime University Hospital with chief complaints of pharyngolaryngeal foreign-body sensation or swallowing difficulties. They were confirmed to be free from any lesion in the pharyngolaryngeal region by routine otolaryngological examination. They were classified into three groups : young group (<40 years in age, n=16) middle aged group (40【less than or equal】 and <65 years, n=48) and elderly group (65 years【less than or equal】, n=39).In the elderly group, pharyngeal clearance of the bolus was significantly impaired than those in young and middle-aged groups Pharyngeal flow and aspiration of the bolus in the elderly group were more frequently observed than in the other groups.2. Pharyngeal manometrySubjects consisted of 14 persons with the age less than 65 years and 35 older than 65 years of age. Pharyngeal pressure was clearly recorded in both groups of age, and the decrease in pressure during the pharyngeal swallowing phase was alsoidentified. However, 34% of subjects in the older group showed lower pharyngeal pressure than normal range, while, none of subjects in the younger group did.This study showed a subclinical impaired swallowing function in the aged population. The change of anatomical structure in the pharyngolarynx was thought to a main explanation.

吞咽功能随增龄变化的评估采用视频透视和测压研究.录像荧光检查受试者包括113人，他们以咽喉异物感或吞咽困难为主诉到爱媛大学医院就诊。经常规耳鼻喉科检查证实，他们的咽喉区域没有任何病变。他们被分为三组：青年组（<40岁，n=16）中年组（40[小于或等于]且<65岁，n=48）和老年组（65岁[小于或等于]，n=39）。在老年组中，咽部清除率明显低于青年组和中年组，老年组老年组咽部血流和吸入食团的发生率高于其他组.咽测压受试者包括14名年龄小于65岁的人和35名年龄大于65岁的人。在两个年龄组中均清楚地记录了咽部压力，并确定了咽部吞咽阶段的压力降低。然而，34%的老年组受试者的咽部压力低于正常范围，而年轻组受试者中无一人低于正常范围。认为咽喉部解剖结构的改变是主要原因。