Vo_2 Kinetics during heavy exercise.

近年来，由于非稳态状态是生物体中较为常见的状态，运动时肺摄氧量(Vo2)动力学作为评价有氧工作能力的新指标受到了广泛关注。通过对稳态和非稳态VO2对运动反应的严格分析，我们能够更深入地了解代谢控制和有氧工作能力的基本机制，它们决定了我们在日常生活中对运动的适应能力。重要的是要弄清静息-运动过渡过程中Vo2反应的确切特征，以及在运动开始后，O2的传递和/或利用是否是Vo2反应的速率限制因素。我们总结了关于上述问题的最新研究，特别是旨在系统地改变(增加/减少)氧输送和/或利用的研究结果，并确定这种扰动对中等运动(结束运动的VO2低于乳酸阈值(LT))和大强度运动(高于LT)的动力学反应的影响。

In recent years, pulmonary oxygen uptake (Vo2) kinetics during exercise have been investigated intensely as a new criterion for the evaluation of aerobic work capacity, since a non-steady state is the more usual condition in organisms. From rigorous analysis of both steady- and non-steady state Vo2 responses to exercise, we are able to gain a deeper insight into the fundamental mechanisms of metabolic control and aerobic work capacity, which determine our adaptability to exercise in daily life. It is of critical importance to clarify both the precise features of the Vo2 response across the rest- exercise transition and whether 02 delivery and/or utilization is the rate-limiting factor in Vo2 response following the onset of exercise. We summarized recent studies on the above issues and, in particular, the results of investigations designed to alter (increase/decrease) oxygen delivery and/or utilization systematically and to determine the effect of such perturbations on the kinetic response of Vo2 to moderate exercise (where end-exercise Vo2 is below the lactate threshold (LT)) and heavy exercise (where it is above LT).