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The Study of Genetic Improvement of Tolerance for Anemia Development and Investigation of Physiological Indicator.

贫血耐受性的遗传改良研究及生理指标调查。

基本信息

批准号：
11660278
负责人：
YAMAGISHI Toshihiro
金额：
$ 2.3万
依托单位：
TOHOKU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1999
资助国家：
日本
起止时间：
1999 至 2000
项目状态：
已结题

项目摘要

(1) We estimated genetic and phenotypic parameters between PCV and calf productivity in the 437 Japanese shorthorn calves. The PCV at pre-grazing (PrePCV), minimum PCV (MinPCV) and daily gain (DG) during grazing were measured from 220, 415 and 400 calves, respectively. Heritabilities of PrePCV MinPCV and DG were estimated 0.61, 0.16 and 0.67, respectively. Simultaneously improvement of anemia tolerance and productivity is expected to be quite feasible. However, this improvement will increase normal PCV, so that some selection criteria to improve anemia tolerance and productivity without the increase of normal PCV are necessary.(2) We examined mutual relationships among the anemia development, liver dysfunction and lipid metabolism and discussed which plasma component was adequate for physiological indicator for genetic improvement of anemia tolerance. By multiple traits analysis, lipid components associated with HDL, phospholipids (PL) and total cholesterol (TC), would closely related anemia development.(3) We estimated genetic and phenotypic parameters between PCV, calf productivity and physiological indicator in the 437 Japanese shorthorn calves, and discussed whether the application of physiological indicator, PL and TC, for genetic improvement was useful or not. Heritabilities of PL and TC were 0.31 and 0.09, respectively. It was suggested that more efficient improvement would realize by introduce physiological indicators into selection indices. PL and TC would be suggested sufficiently useful indicators for genetic improvement of anemia tolerance.

(1)对437头日本短刺牛的PCV与产仔率之间的遗传和表型参数进行了分析。分别测定220头、415头和400头犊牛放牧前PCV （PrePCV）、最小PCV （MinPCV）和放牧期间日增重（DG）。预估的precv、MinPCV和DG遗传力分别为0.61、0.16和0.67。同时提高贫血耐受性和生产力是可行的。然而，这种改善会增加正常的PCV，因此有必要制定一些选择标准，在不增加正常PCV的情况下提高贫血耐受性和生产力。(2)探讨了贫血发生、肝功能障碍和脂质代谢之间的相互关系，并讨论了哪种血浆成分适合作为贫血耐受性遗传改善的生理指标。通过多性状分析，与HDL、磷脂（PL）和总胆固醇（TC）相关的脂质成分与贫血的发生密切相关。(3)估算了437头日本短刺犊牛PCV、产仔率和生理指标之间的遗传和表型参数，探讨了生理指标PL和TC在遗传改良中的应用效果。PL和TC的遗传力分别为0.31和0.09。在选择指标中引入生理指标可以实现更有效的改良。PL和TC可作为贫血耐受性遗传改良的有用指标。