The influence of endocrine disrupting substances on the disorder of male external genitalia

我们遇到了环境问题，尤其是影响地球生物的内分泌干扰物质。这些物质已被描述为诱发性别分化障碍。在美国，由于内分泌干扰物质的影响，雄性短吻鳄的阴茎往往短小畸形。在日本，二恶英是最著名的内分泌干扰物质之一，由焚化炉产生。据报道，尿道下裂的发生率越来越高，这与胎儿内分泌问题有关。我们调查了五名妇女，并检查了她们的儿子患有尿道下裂的阴茎障碍，她们的血液中二恶英的含量。他们所有的儿子都在5岁和5岁以下。对照组与母亲血液中二恶英含量无显著差异。

We encounter environmental problems, especially endocrine disrupting substances which affects living things on earth. These substances have been described to induce disorders about sex differentiation. Male alligators tended to have tiny penis with deformity because of endocrine disrupting substances in the US.In Japan dioxin has been one of the most famous endocrine disrupting substances which is produced at incinerators. It was reported that the incidence of hypospadias was increasing which is caused by somewhat endocrine problems in fetus. We investigated five women and examined the dioxin level in blood whose boys suffered from penile disorder called hypospadias. All of their boys were under five and five years old. There was no significant difference between general controls and the motehrs as for the dioxin level in blood.