Endurance training enhances adaptability of RBC

耐力训练增强红细胞适应性

• 批准号: 11680053
• 负责人: IWAGAKI Suketsune
• 金额: $ 2.05万
• 依托单位: Tokai University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11680053/
• 关键词: Endurance training; MCV; Plasma PC; Catecholamine; RBC membrane PC; Ch; PC ratio; Fluidity of RBC membrane; Adaptability of RBC; RBC; Exhaustion exercise; 血液インキュベーション; MCH; plasma HDL; MCV-plasmaHDL関係; 長距離選手; performance

Endurance ability of distance runners has been evaluated by maximum oxygen uptake. However, this relationship is not established in elite distance runners. We investigated characteristics of RBC indexes with endurance training to clarify this background. First, we found contradiction between RBC and performance ; longitudinal study on RBC indexes of distance runners for 4 years indicated significant decrease of RBC and blood viscosity with endurance training. From viewpoint of oxygen uptake, decrease of RBC with endurance training is a negative factor, but improvement of their performances occurred. In the background, compensatory increases of MCV and MCH significantly occurred at the time. We estimated relationship between RBC membrane and plasma lipids, because there are many phospholipids in plasma HDL which are composed of cell membrane. There were significan relationships between plasma HDL and MCV.However, a half of the distance runners did not show such relationship. Since there … More is a significan relationship between RBC membrane and plasma PCs via LCAT activity, we investigated relationship between plasma PC and plasma HDL.The relationship between them was not linear. The plasma PC in significant relationship group between MCV and plasma HDL was significantly higher that those in no-significant group. Then, amount of plasma PC directly influenced on establishment of the relationship between MCV and plasma HDL.From these results, the compensatory increase of MCV with endurance training was supported with amount of plasma PC and meant increase of RBC membrane PC ; increase of membrane fluidity and RBC adaptability. The mechanism on increase of MCV was studied by exhaustive exercise, addition catecholamine and mechanical stimulation. From these results, increase of the RBC membrane PC were obtained. Increase of RBC membrane PC suggests that decrease of Ch/PC ratio in RBC membrane enhances membrane fluidity and adaptability of RBC.In this sense, we demonstrated the exercise or training was essential for RBC itself to maintain the better structure and function. Less

中长跑运动员的耐力能力是以最大摄氧量来评价的。然而，这种关系在优秀长跑运动员中并不成立。我们研究了耐力训练时红细胞指标的特征，以阐明这一背景。首先，我们发现了红细胞与运动成绩之间的矛盾，对中长跑运动员红细胞指标进行了4年的纵向研究，结果表明，随着耐力训练的进行，红细胞和血液粘度显著下降。从摄氧量的角度来看，耐力训练使红细胞下降是一个负面因素，但运动成绩却有所提高。在背景中，MCV和MCH的代偿性增加在此时显著发生。由于血浆HDL中含有大量的磷脂，是由细胞膜组成的，因此我们推测了红细胞膜与血浆脂质之间的关系。血浆HDL与MCV之间存在显著的相关性，但有一半的中长跑运动员不存在这种相关性。由于 ...更多信息 红细胞膜与血浆PC之间通过LCAT活性的变化存在着显著的相关性，本文研究了血浆PC与血浆HDL之间的关系，发现二者之间并不呈线性关系。MCV与HDL显著相关组血浆PC显著高于无显著相关组。血浆PC含量直接影响MCV与血浆HDL之间关系的建立，说明耐力训练后MCV的代偿性增加与血浆PC含量、红细胞膜PC含量、膜流动性和红细胞适应性的增加有关。通过力竭运动、补充儿茶酚胺和机械刺激等方法，探讨了运动后MCV增加的机制。从这些结果中，获得了RBC膜PC的增加。红细胞膜PC的增加提示红细胞膜Ch/PC比值的降低增强了红细胞膜的流动性和适应性，从这个意义上说明运动或训练对维持红细胞自身良好的结构和功能是必要的。少

项目成果

岩垣丞恒: "Reexamination of changes in plasma lipids plasma incubation"Advances in Exercise and Sport physiology. 4(4). 156 (1999)

Joko Iwagaki：“血浆脂质变化的重新检查”运动和运动生理学进展 4(4) (1999)。

岩垣丞恒: "「東京箱根間往復大学駅伝競走に関する総合的研究」"東海大学スポーツ医科学研究所報告書. 1-45 (2000)

岩垣让子：“东京和箱根往返大学接力赛的综合研究”东海大学运动医学研究所报告1-45（2000）。

岩垣丞恒: "長距離選手における赤血球MCVとplasma HDL関係"東海大学スポーツ医科学. 13号(印刷中). (2000)

Joko Iwagaki：“长距离运动员红细胞 MCV 和血浆 HDL 之间的关系”，东海大学运动医学第 13 期（出版中）。

Suketsune, Iwagaki: "Longitudinal changes in RBC inclines of student long distance runners"Advances in Exercise and Sports Physiology. 4(4). -153 (1999)

Suketsune, Iwagaki：“学生长跑运动员红细胞倾斜度的纵向变化”运动和运动生理学进展。

岩垣丞恒: "スポーツ医科学研究プロジェクト研究報告"東海大学スポーツ医科学. 11. 79-90 (1999)

Joko Iwagaki：“运动医学研究项目报告”东海大学运动医学11. 79-90（1999）。