New Approaches to Understand How Form and Function Shape Complex Systems

理解形式和功能如何塑造复杂系统的新方法

• 批准号: FL210100110
• 负责人: Prof Helen Byrne
• 金额: --
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Australian Laureate Fellowships
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-07-01 至 2023-04-18
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FL210100110
• 关键词: New; Approaches; Understand; How; Form

As biology and medicine transform into quantitative sciences, existing mathematical methods are often inadequate to explain the data they generate. This project aims to unlock the potential of such biomedical data through the development of new mathematical approaches that combine concepts from pure and applied mathematics, statistics and data science, and then to investigate their ability to generate mechanistic insight into fundamental biomedical processes. In this way, the project expects to affect a paradigm shift in mathematical biology while strengthening Australia’s reputation as a world-leader in mathematical biology. An outcome from this project could be new mathematical models that guide decision making in the clinic.

随着生物学和医学向定量科学的转变，现有的数学方法往往不足以解释它们产生的数据。该项目旨在通过开发新的数学方法来释放这种生物医学数据的潜力，这些方法将纯数学和应用数学、统计学和数据科学的概念联合收割机结合起来，然后研究它们对基本生物医学过程产生机械见解的能力。通过这种方式，该项目预计将影响数学生物学的范式转变，同时加强澳大利亚作为数学生物学世界领导者的声誉。该项目的成果可能是指导临床决策的新数学模型。