Properties and Reaction of π-Conjugated Carbonyl Compounds

我们的研究结果如下：1.新的固态性质：托波酮以酮式和烯醇式的最终平衡混合物存在。特罗普隆在溶液中的平衡速度极快，但在固体中的平衡在核磁共振时间尺度上冻结。硫代妥普隆是硫磺类似物。我们发现，无论是在溶液中还是在固体中，该化合物都以极快的平衡混合物存在。这种新的固态行为被发现是由于单硫代谢物的堆积排列所致。在活化的三钙化合物与活化的亚甲基化合物的反应中合成天青烯：活化的肌钙化合物与活化的亚甲基化合物反应以良好的产率得到偶氮烯。这些反应是获得具有五元环上多官能团的氮烯衍生物的有效方法。研究了2-甲氧基托酮与丙二醛反应生成天青烯的反应机理，找到了包括几个平衡过程在内的多步反应的详细路径。

We have found the following results,1. Novel solid-state propertie :Tropolone exsits as an last equilibrium mixture of a ketone form and an enol form. This equilibrium of tropolone is extremely fast in solution, but is frozened on the NMR time scale in the solid state. Monthiotropolone is the sulfur analogue of tropolone. We have found that this compound exists as extremely fast equilibrium mixture both in solution and in the solid state. This novel behavior in the solid-state is found to be due to packing arrangement of monothiotropolone.2. Azulene synthesis in the reaction of an activated trponoid compound with an activated methylene compound :Reaction of activated troponoid compounds with activated methylene compounds gave azulenes in good yields. These reactions are useful methods to obtain azulene derivatives with polyfunctional groups in five-membered ring moiety. We investigated the reaction mechanism of 2-methoxytropone with malonouilrilc to give an azulene and found the detailed reaction path of many steps containing several equilibrium processes.