Establishment of non-invasive examination of swallowing patterns and changes in electrogastrogram during normal swwallowing.

本研究旨在建立正常吞咽模式的非侵入性检查，并阐明正常吞咽过程中胃动力的变化。结果如下：（1）为了解正常人的吞咽模式，我们观察了自发吞咽时的喉运动、吞咽音和鼻腔温度。此外，在正常成人中研究了颈部位置和丸剂体积对这些参数的影响。主动吞咽是由红灯触发的。与10 cc水相比，受试者吞咽20 cc水时喉运动和吞咽呼吸暂停的持续时间显著延长。与前屈20 °组相比，背屈10 °组喉运动延迟和吞咽呼吸暂停时间明显缩短，喉运动持续时间明显延长。结果提示，正常人喉、腭位保持抬高， 关于我们 olle以防止由于大剂量而导致的误吞咽。水在背屈时迅速流入喉。因此，它进一步表明，受试者缩短喉和软腭运动和延长喉抬高时，他们在背屈吞咽的开始。(2)为了解正常吞咽时胃运动的变化，记录了自发吞咽和注射各种溶液引起的吞咽反射时的胃电图（EGG）。当受试者吞咽20cc水时，食管扩张可使EGG振幅一过性增加。咽部注射0.05%柠檬酸、水和0.9%氯化钠可引起胃电振幅的一过性增加。EGG的幅值按柠檬酸>水> NaCl的顺序增加。吞咽反射潜伏期缩短的顺序为柠檬酸>水> NaCl。结果提示，胃运动受咽、喉区机械和化学刺激的影响。少

This study was conducted to establish non-invasive examination of normal swallowing patterns, and to clarify gastric motility changes during normal swallowing. The results were as follows :(1) To examine normal patterns of swallowing, we investigated laryngeal movement, sound associated with swallowing and temperature of nasal cavity during voluntary swallowing. Furthermore, effects of cervical position and bolus volume on these parameters were investigated in normal adults. Voluntary swallowing was triggered by onset of a red lamp. Duration of laryngeal movement and deglutition apnea were significantly elongated when subjects swallowed 20cc water compared with 10cc water. In 10 degree dorsiflexion, latencies of laryngeal movement and deglutition apnea were significantly shortened and duration of laryngeal movement was elongated compared with those in 20 degree anteflexion. From these findings, it was suggested that healthy subjects retained at elevated position of larynx and palatum m … More olle to prevent misswallowing due to large volume of bolus. Water rapidly flowed into larynx in dorsiflexion. Thus, it was further suggested that subjects shortened onset of larynx and palatum molle movement and elongated laryngeal elevation when they swallowed in dorsiflexion.(2) To clarify changes in gastric motility associated with normal swallowing, elctrogastrogram (EGG) was recorded during voluntary swallowing and swallowing reflex elicited by injection of various solution. Amplitude of EGG was transiently increased by dilation of esophagus when subjects swallowed 20cc water. Injection of 0.05% citric acid, water and 0.9% NaCl into pharynx induced transient increase of amplitude of EGG. The amplitude of EGG increased in the order of citric acid > water > NaCl. The latency of swallowing reflex was also shortened in the order of citric acid > water > NaCl. From these findings, it was suggested that gastric motility is influenced by mechanical and chemical stimulation to pharyngeal and laryngeal region. Less