Comparative and Histogenetics study on origin, development and evolution of enamel structure on human tooth

人类牙齿釉质结构起源、发展和演化的比较和组织遗传学研究

• 批准号: 12671787
• 负责人: KOZAWA Yukishige
• 金额: $ 2.05万
• 依托单位: Nihon University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671787/
• 关键词: enamel structure; Hunter-Schreger band; enamel prism; enamel organ; ameloblast grouping; ameloblast dancing; histological evolution; immunocytology; シュレーゲル条; エナメル芽細胞; grouping; dancing; エナメル質; 立体構築; 歯胚; 発生; 組織進化; シューレーゲル条

The origin and the development of the enamel structure were examined, and the meaning was discussed.The ameloblasts of crocodilian enamel forms groups (Grouping) admitted to the crystal unit in enamel. The boundary of each crystal unit is not corresponding to boundaries of the ameloblasts groups, and also differenced to the boundary of Hunter-Schreger band. It is clear that the boundary relates to the enamel tuft and lamella of mammalian enamelThe enamel prism in primitive mammals shows winding run with disappearance of enamel tubules along with the development. It is suggested the movement of the ameloblast is influenced (or controled) by the odontoblastic process. The Hunter-Schreger band appears as sets of islanded of enamel prisms groups in primitive mammals as compare from fossil to resent mammals. The island prism groups expand horizontal direction where the tooth crown is surrounded. The expanding patterns were variable in each mammalian species, but horizontal type of Hunter-Sc … More hreger band is basic pattern in many mammals. This was named 'Grouping' of the enamel prism. The enamel prism runs not only in one zones of Hunter-Schreger band but also changes the course one to the other zones. Other enamel prism pattern runs only the boundary of zones. This was named 'Dancing' of the enamel prism.In an examination of tooth germs of dog etc. with the immunocytochemical method, the localization of the actin showed the grouping form in the outer enamel epithelium, stellate reticulum, stratum intermedium, and ameloblasts as Hunter-Schreger bands.The keratins showed similar localization of 'Grouping' of the enamel prism. It is clear that that grouping and moving of enamel organ forms the Hunter-Schreger bands.The actin localization in Tome's process of amelobast showed original movement besides grouping. It is showed that the dancing of Tome's process formed the patterns of enamel prism arrangement, so called 'Dancing'Further studies to clarify the factor to control these movements will have done in the future. Less

本文探讨了釉质结构的起源和发展，并讨论了其意义。各晶体单位的边界与成釉细胞群的边界不一致，与Hunter-Schreger带的边界也不一致。原始哺乳动物的釉柱呈弯曲状，随着发育，釉小管沿着消失。提示成釉细胞的运动受成牙本质细胞过程的影响或控制。从化石到现代哺乳动物，Hunter-Schreger带在原始哺乳动物中表现为一组岛状的釉质棱柱群。岛状棱柱组在牙冠周围水平方向扩展。各种哺乳动物的扩张模式不同，但水平型的Hunter-Sc ...更多信息 Hreger带是许多哺乳动物的基本带型。这被命名为“釉棱镜”。釉棱柱不仅在Hunter-Schreger带的一个区域内运行，而且还改变了一个区域到其他区域的路线。其他搪瓷棱镜模式运行只有边界的地区。用免疫细胞化学方法观察狗等牙胚，肌动蛋白在外釉上皮、星网状层、中间层和成釉细胞中的定位呈Hunter-Schreger带的群聚形式，角蛋白在釉棱柱中也呈类似的“舞蹈”定位。成釉细胞托姆突的肌动蛋白定位除成釉细胞成釉外，还表现出原始运动。结果表明，托姆突的"舞蹈“形成了釉柱排列的模式，即”舞蹈“。少

项目成果

三島弘幸: "マイクロフォーカスX線CT装置を用いたヒト小臼歯の三次元再構築像の観察"日大口腔科学. 26巻3号. 244-248 (2000)

Hiroyuki Mishima：“使用微焦点 X 射线 CT 设备观察人体前磨牙的三维重建图像”，日本大学口腔科学，第 26 卷，第 3 期，244-248（2000 年）。

小澤幸重: "健康のバロメーター 歯と骨を探る…人体の中の鉱物"Crystal Letters. 19. 20-24 (2002)

Yukishige Ozawa：“健康晴雨表：探索牙齿和骨骼......人体内的矿物质”《水晶快报》19. 20-24 (2002)。

小澤 幸重: "カラーアトラス 口腔組織発生学"わかば出版. 1-114 (2001)

Yukishige Ozawa：《口腔组织胚胎学彩色图谱》Wakaba Publishing 1-114 (2001)。

Y.Kozawa: "Morphology of Nerve Ending and It's 3-D Distribution in Periodontal Ligament an Alligator (Caiman Crocodilius)"X V International Symposium on Morphological Sciences. 142 (2000)

Y.Kozawa：“鳄鱼（凯门鳄）牙周膜神经末梢的形态及其 3-D 分布”第 5 届国际形态科学研讨会。

C. Sasaki: "Apoptosis in regressive deciduous tooth germs of Suncus murinus evaluated by the TUNEL method and electron microscopy"Archives of oral biology. 46. 649-660 (2001)

C. Sasaki：“通过 TUNEL 方法和电子显微镜评估 Suncus murinus 退化乳牙胚的细胞凋亡”口腔生物学档案。