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Development and dental application of novel low viscous monomers

新型低粘度单体的开发及牙科应用

基本信息

批准号：
12671907
负责人：
MIYASAKA Taira
金额：
$ 1.79万
依托单位：
THE NIPPON DENTAL UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2002
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671907/
关键词：
low viscous monomer base monomer bis-GMAD type monomer composite resin mechanical property synthesis light curing ジメタクリレート低粘度物性重合体

项目摘要

Novel monomers with relatively low viscosity were synthesized and investigated to accurate the possibility of the dental use as a base monomer for composite resin or adhesive cement. Such monomers have no need to use diluent monomers which possibly cause to weaken over all mechanical properties of cured materials.As the monomers whose center of skeletal structures have one or two less carbon than bis-GMA, and methacrylate derivatives of bis-phenol AD epoxy monomer, 1,1-bis[4-(2-hydroxy-3-methacryloyloxypropoxy)-phenyl]ethane (monomer 1) and bis-[4-(2-hydroxy-3-methacryloyloxy-propoxy)phenyl]methane (monomer 2) were synthesized. The viscosities of the monomers were measured, then mechanical properties of the polymers obtained from light curing of the monomers were investigated and some mechanical properties of hybrid filled light curing composite resins made from these monomers were also investigated. The following conclusions were drawn.1)The viscosities of monomer 1 and 2 were relatively significantly smaller than that of bis-GMA.2)Monomer 1 and 2 can be polymerized easily by usual light induced initiators.3)The polymer obtained from the monomer 1 has almost the same strength of that obtained from bis-GMA and TEGDMA monomer mixture.4)The light curing composite resins containing hybrid fillers were obtained.5)The mechanical properties of the experimental composite resins, were the same level as those of bis-GMA and TEGDMA comonomer.From above conclusions, monomer 1 seemed to hold great promise for the use of the base monomer of dental composite resin or dental adhesive cements.

合成了具有较低粘度的新型单体，并对其进行了研究，以确定其在牙科中作为复合树脂或胶粘剂水泥的基础单体的可能性。这种单体不需要使用稀释单体，因为稀释单体可能会削弱固化材料的所有机械性能。作为骨架结构中心比双gma少一个或两个碳的单体，以及双酚AD环氧单体的甲基丙烯酸酯衍生物，合成了1,1-双[4-（2-羟基-3-甲基丙烯酰氧基丙氧基）苯基]乙烷（单体1）和双[4-（2-羟基-3-甲基丙烯酰氧基丙氧基）苯基]甲烷（单体2）。测定了这些单体的粘度，研究了光固化所得聚合物的力学性能，并研究了由这些单体制备的杂化填充光固化复合树脂的力学性能。得出了以下结论。1)单体1和单体2的粘度相对显著小于bis-GMA。2)单体1和2可以用普通的光引发剂容易聚合。3)由单体1得到的聚合物与由双gma和TEGDMA单体混合物得到的聚合物具有几乎相同的强度。4)制备了含杂化填料的光固化复合树脂。5)实验复合树脂的力学性能与双gma和TEGDMA共聚物的力学性能相同。综上所述，单体1有望成为牙科复合树脂或牙科胶粘剂水泥的基础单体。