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Estimation of the body fluid shift by the multi-frequency admittance method

多频导纳法估计体液转移

基本信息

批准号：
12680843
负责人：
SAKAMOTO Katsuyuki
金额：
$ 2.05万
依托单位：
KITASATO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2003
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680843/
关键词：
fluid removal intra-and extra-cellular fluid economy syndrome fat volume finite element method boundary element method Col-Col distribution shadow effect インピーダンスCT 体脂肪組織電気アドミタンス 3次元境界要素法下肢アドミタンスの周波数特性自律神経系細胞形状変化細胞内外液量変化

项目摘要

1) Economy syndromeI produce the new algorism for estimating the change volume in leg.I measured legs electrical admittance and estimated blood volume change, intra and extra-cellular fluid volume change in legs, when volunteers were sitting for 1 hour. There were no intra and extra-cellular fluid change in leg.2) Fluid removal during artificial dialysisI obtained the new good algorism for estimating fluid removal during artificial dialysis.I obtained that the estimated fluid removal agreed well with the measured fluid removal. We also estimated intra and extra-cellular fluid volume change during artificial dialysis.3) Estimation of fat volumeI theoretically discussed the electrode arrangement for measuring fat volume in stomach. We calculated the potential distribution on the surface of the body under the various electrode arrangements.4) Basic study of tissue admittance by finite element methodIntra and extra-cellular fluid admittance are obtained from the measured admittance loci. Shadow effect is very large at low frequency Therefore, measured admittance at low frequency is underestimated. I obtained the following results. When the concentration of cells is low, this effect is large. On the other hand, the concentration of cells is high, the effect is small.5) Basic study of tissue admittance by boundary element method (BEM)Measured time constant of living tissue just shows the Col-Col distribution. From calculation results, I concluded that cell membrane capacitance greatly contributes greatly to the Col-Col distribution.

1)经济综合征我提出了一种新的计算下肢变化量的算法，测量了志愿者在坐位1小时时的下肢电导纳，并计算了下肢血容量变化、细胞内液和细胞外液容量变化。2）人工透析过程中的液体排出量我得到了一个新的估算人工透析过程中液体排出量的良好算法，得到了估算的液体排出量与测量的液体排出量的一致性。我们还估计了人工透析过程中细胞内和细胞外液体体积的变化。3）脂肪体积的估计我从理论上讨论了测量胃脂肪体积的电极布置。4）组织导纳的有限元法基础研究由测量的导纳轨迹得到了细胞内和细胞外流体的导纳。低频时阴影效应很大，因此低估了低频时的实测导纳。我得到了以下结果。当细胞浓度低时，这种效应很大。另一方面，细胞浓度高，影响小。5）边界元法（BEM）对组织导纳的基础研究活体组织时间常数的测量结果正好反映出Col-Col分布。计算结果表明，细胞膜电容对Col-Col分布的影响很大。