Engineering of biocatalysis in metal-organic frameworks for CO2 conversion

将温室气体二氧化碳（CO2）转化为有价值的燃料将有利于缓解能源短缺和提高全球可持续性。该项目旨在在金属有机框架（MOFS）中构建一个生物级联系统，用于人工二氧化碳转化。从生物体中学习，包括酶和辅因子的整个生物催化单元将被包裹并保护在人造多孔聚合物MOF涂层中。这种方法预计将提供强大的生物催化剂，具有高反应活性和化学选择性，在工业操作条件下将CO2转化为甲醇，包括热，pH值和化学应激。这一进步将有助于实现碳中和的工业和社会。

Transforming the greenhouse gas carbon dioxide (CO2) into valuable fuels would be beneficial for relieving energy shortage and improving global sustainability. This project aims to architect a biocascade system in metal-organic frameworks (MOFs) for artificial CO2 conversion. Learned from the living organisms, a whole biocatalysis unit including enzymes and cofactors will be encased and protected in an artificial porous polymeric MOF coating. This approach is expected to deliver robust biocatalysts with high reaction-activity and chemo-selectivity in converting CO2 into methanol under the industrial operating condition, involving thermal, pH, and chemical stressors. This advancement will contribute to a carbon-neutral industry and society.