Design of new ion association reagents having light absorption and thermo-dependence and analysis of ion association mechanism

1)吨染料如曙红和四碘荧光素在pH 7-9下与季铵离子形成1：2离子缔合;然而，在有机溶剂中显色较差。在中性介质中，当氧杂蒽染料与金鸡纳生物碱形成1：2的可萃取缔合物时，加入季铵盐，形成1：1：1的混合三元离子缔合物。其可萃取性由于更大体积的缔合形成而增强。金鸡纳生物碱的加入引起的离子缔合是独特的。曙红和四碘荧光素可用于测定痕量季铵盐。2）在1，10-phen存在下，半胱氨酸与铁（III）的缓慢氧化还原反应在铜（II）催化下生成铁（II）-phen络合物。检测限（3σ）为5 × 10 - <-7>4 M，RSD为0.4%。然而，许多其他氨基酸不干扰， ...更多信息 还原性和氧化性物质产生强烈干扰。同时，建立了一种在双光束分光光度计上安装双流动池的流动注射分光光度法同时测定抗坏血酸和半胱氨酸的方法。铜（II）大大加速了铁（III）与半胱氨酸的还原反应，而与抗坏血酸的还原反应受铜（II）的影响很小。根据两种反应速率的差异，可同时测定两种物质。3）建立了同时测定药用季铵盐和芳香胺的分步滴定法。用四溴酚酞乙酯（TBPE）萃取R_4N和R_3NH，建立了一种新的分离R_4N和R_3NH的方法。用四（4-氟苯基）硼酸盐或四苯硼酸盐滴定含这些化合物的样品时，有机相的颜色变为蓝色、红紫色和黄色，分别确定了第一终点和第二终点。少

1) Xanthene dyes such as eosin and tetraiodofluorescein form 1 : 2 ion associates with quaternary ammonium ions at pH 7-9 ; however, the development of color in the organic solvent is poor. When a quaternary ammonium salt is added in the etractable 1 : 2 associate formed between a xanthene dye and a cinchona-alkaloid in the neutral media, a mixed ternary ion associate (1 : 1 : 1) is formed. Its extractability is enhanced due to the more bulky association formation. The ion association caused by addition of cinchona-alkaloids is unique. Eosin and tetraiodofluorescein are useful for the determination of trace amounts of quaternary ammonium salts.2) The slow redox reaction of cysteine with iron(III) in the presence of 1,10-phen is catalyzed by copper(II), producing an iron(II)-phen complex> The color development is applied to the determination of cysteine spectrophotometrically. The limit of detection(3σ) is 5 x 10^<-7> M and RSD is 0.4%. Many other amino acids do not interfere, however, … More reducing and oxidizing substances gave strong interferences. And also, a spectrophotometric method was developed for the simultaneous analysis of ascorbic acid and cysteine by flow injection system equipped with a double flow cell, which was installed in a double-beam spectrophotometer. Copper(II) greatly accelerated the reduction reaction of iron(III) with cysteine, while with ascorbic acid was little affected by copper(II). On the basis of the difference in the rate between the two reactions, both substances can be determined.3) Stepwise titrimetric method is developed for the simultaneous determination of pharmaceutical quaternary ammonium salts and aromatic amines. The method is based on the solvent extraction of R_4N and R_3NH with an ion association reagent, tetrabromophenolphthalein ethyl ester (TBPE). When the samples containing these compounds are titrated with tetrakis(4-fluorophenyl) borate or tetraphenylborate, the color in organic phase turned to blue, red-violet and yellow and the first end point and second end point were determined, respectively. Less