权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Thoracoscopic treatment of atrial fibrillation on the beating heart

胸腔镜治疗心脏跳动的房颤

基本信息

批准号：
13671377
负责人：
KUBOTA Hiroshi
金额：
$ 2.3万
依托单位：
Kyorin University (2002-2003)The University of Tokyo (2001)
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2003
项目状态：
已结题

项目摘要

Recently, surgical treatment of arrhythmia has been widespread. Especially, the surgical treatment of the atrial fibrillation : MAZE procedure has been noticed and has been done by many cardiac surgeon. This procedure can cure the atrial fibrillation by means of cutting and sewing both atrium to recover sinoatrial conduction. However, there are several drawbacks e.g. complicated cutting line, prolongation of the aortic crosclamp time, bleeding. Instead of cut and sew technique, other ablation devices have been developed to solve these problems, there is no device which solve all of these problems. We focused on cryoablation and infrared coagulation systems.Epicardial cryoablation technique (LAVIE) was applied to seven patients. All patient except one has recovered sinus rhythm several weeks after the procedure spontaneously. These are the first cases in the world and presented in The Annals of Thoracic Surgery in 2004. The efficacy of the infrared coagulator also demonstrated in the animal experience using canine and the results will be published in The Annals of Thoracic Surgery this year.The first clinical application of infrared coagulator has been done in 2005, however it failed because of the carbonization of the atrial tissue. We noticed that not only the ablation duration but also energy output is important to control the depth of coagulation, and modified the coagulator to be an energy output controllable one.These results were presented at the 20^<th> Meeting of Japanese pacing and electrophysiological Society in May 2005.The latest model of infrared coagulator is ready to use clinically.

近年来，心律失常的外科治疗已得到广泛应用。特别是心房颤动的外科治疗：迷宫术已引起许多心脏外科医生的注意，并已被许多心脏外科医生所采用。该术式是通过切开并缝合双心房，恢复窦房传导，从而达到治疗心房颤动的目的。但其存在切割线复杂、主动脉阻断时间延长、出血等缺点。已经开发了其他消融器械来代替切割和缝合技术来解决这些问题，但没有一种器械可以解决所有这些问题。我们重点介绍了冷冻消融和红外线凝固系统，并对7例患者应用了心外膜冷冻消融技术（LAVIE）。除一名患者外，所有患者在手术后数周自行恢复窦性心律。这些是世界上第一例，并于2004年在胸外科年鉴上发表。2005年，红外线电凝器首次应用于临床，但因心房组织碳化而失败。在2005年5月召开的日本起搏与电生理学会第20届年会上，我们注意到控制凝固深度不仅要控制消融时间，而且要控制能量输出，并将其改进为能量输出可控的凝固器<th>。