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Studies of data-collecting strategies for the literature database on diagnostic characteristics of laboratory examination and structural design of the database

实验室检查诊断特征文献数据库数据收集策略研究及数据库结构设计

基本信息

批准号：
13672436
负责人：
ISHIDA Haku
金额：
$ 2.3万
依托单位：
Yamaguchi University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2003
项目状态：
已结题

项目摘要

The search strategy in identification of the articles related to diagnostic accuracy and a structure of database were investigated for performing systematic review in laboratory medicine efficientlyWhen retrieval of article from MEDLINE was performed to identify articles listed in published systematic reviews, the rate of identification of them varied greatly according to the difference in usage of keyword such as MeSH, subheading term or text words. Therefore, in systematic review, in order to perform highly sensitive search without an overlooking, careful thinking for combination of searching terms such as "sensitiv*", "specificit*", "diagnos*" and nomenclature of diagnostic test itself was required based on the result of retrieval investigated by Haynes and others. Moreover, as the structure of a database for systematic review, the database consisting of the following components was considered as suitable : literature information of primary articles, information about summary of sys … More tematic review, additional information on the quality and external validity of literature, diagnostic accuracy, and index information such as MeSHBased on the database structure, knowledge database with Web interface was developed in order to perform systematic reviews efficiently and continuously through collaborative actions by researchers and the following functions were mounted : 1) displaying articles that have been appraised critically ; 2) a page for registration of literature information of study reports on the database and a page for critical appraisal ; 3) a page for entry of diagnostic characteristics and a function of automatic calculation of confidential intervals ; 4) an input/output page for group-based systematic review ; 5) extraction of information for meta-analyses and graphs (Forest plot and summary ROC curves) : and 6) a page for registration of unpublished studies and a page for editing abstracts. Moreover, the check list for critical appraisal was improved according to the differences between the previous one and other tools such as STARD initiativeMembers of our study group and other collaborative reviewers entered data into this database to evaluate the integrity of the system and reported the system Less

为了更有效地进行检验医学系统评价，对与诊断准确性相关的文献的检索策略和数据库结构进行了研究。当从MEDLINE检索文献以识别已发表的系统评价中的文献时，根据关键词如MeSH、副标题术语或正文词的使用差异，识别率有很大差异。因此，在系统评价中，为了进行高灵敏度检索而不被忽视，需要根据Haynes等人研究的检索结果仔细考虑检索术语的组合，如“敏感性 *"、“特异性 *"、“诊断 *”和诊断试验本身的命名。此外，作为系统评价数据库的结构，由以下组成的数据库被认为是合适的：主要文章的文献信息，系统综述的信息， ...更多信息系统评价、文献质量和外部有效性的附加信息、诊断准确性和索引信息（如MeSH）基于数据库结构，开发了具有Web界面的知识数据库，以便通过研究者的协作行动有效地和连续地进行系统评价，并安装了以下功能：1）显示已被批判性评价的文章; 2）数据库中研究报告文献信息登记页面和批判性评价页面; 3）诊断特征输入页面和自动计算置信区间功能; 4）基于组的系统评价输入/输出页面; 5）荟萃分析和图表信息提取（森林图和ROC曲线汇总）：6）未发表研究登记页面和摘要编辑页面。此外，根据之前的工具与其他工具（如STARD倡议）之间的差异，改进了关键评估的检查表。我们研究小组的成员和其他合作评审员将数据输入该数据库，以评估系统的完整性并报告系统。