Studies of data-collecting strategies for the literature database on diagnostic characteristics of laboratory examination and structural design of the database

点击翻译按钮获取中文摘要

The search strategy in identification of the articles related to diagnostic accuracy and a structure of database were investigated for performing systematic review in laboratory medicine efficientlyWhen retrieval of article from MEDLINE was performed to identify articles listed in published systematic reviews, the rate of identification of them varied greatly according to the difference in usage of keyword such as MeSH, subheading term or text words. Therefore, in systematic review, in order to perform highly sensitive search without an overlooking, careful thinking for combination of searching terms such as "sensitiv*", "specificit*", "diagnos*" and nomenclature of diagnostic test itself was required based on the result of retrieval investigated by Haynes and others. Moreover, as the structure of a database for systematic review, the database consisting of the following components was considered as suitable : literature information of primary articles, information about summary of sys … More tematic review, additional information on the quality and external validity of literature, diagnostic accuracy, and index information such as MeSHBased on the database structure, knowledge database with Web interface was developed in order to perform systematic reviews efficiently and continuously through collaborative actions by researchers and the following functions were mounted : 1) displaying articles that have been appraised critically ; 2) a page for registration of literature information of study reports on the database and a page for critical appraisal ; 3) a page for entry of diagnostic characteristics and a function of automatic calculation of confidential intervals ; 4) an input/output page for group-based systematic review ; 5) extraction of information for meta-analyses and graphs (Forest plot and summary ROC curves) : and 6) a page for registration of unpublished studies and a page for editing abstracts. Moreover, the check list for critical appraisal was improved according to the differences between the previous one and other tools such as STARD initiativeMembers of our study group and other collaborative reviewers entered data into this database to evaluate the integrity of the system and reported the system Less