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Physiological polymorphisms in response to environmental factors of light and ambient temperature and its human adaptability

光、环境温度等环境因子的生理多态性及其人体适应性

基本信息

批准号：
15107006
负责人：
YASUKOUCHI Akira
金额：
$ 68.47万
依托单位：
Kyushu University (2004-2007)九州芸術工科大学 (2003)
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (S)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2007
项目状态：
已结题

项目摘要

1. By clarifying the effects of fluorescent and LED light spectra in each on the individual difference of papillary response, we obtained the important data on the appropriate spectral distribution of the light sources with regard to their effects on nocturnal melatonin release.2. Light reflection of the wall under the same light source revealed that wooden materials that absorbed the component of short-wave length elicited a less melatonin suppression rate than other materials.3. The light-induced melatonin suppression rate measures light sensitivity of biorhythm, the light-sensitive mechanism in humans is enhanced in response to insufficient daylight illumination in winter while typical light/pale irises at high-latitude regions accommodate to enhance light-sensitivity of the circadian system. Therefore, the significance of these mechanisms is to prevent depression and relevant health problems associated with insufficient seasonal daylight exposure.4. The effects of the living factor … More s attenuating the basal metabolic rate on cold tolerance were clarified; i.e. the factors and their relevant physiological polymorphism with environmental adaptation. Based on correlations with the survey of living-habits, guidelines on living activity to improve cold tolerance were formulated.5. With reference to the subjective perception of hot- or cold-sensitive perspectives of one self, quantitative results of skin and core temperatures and subjective data under the same room conditions revealed that subjective assessments might not necessary reflect environmental adaptation from the aspect of physiological response when differences in gender, age and season were taken into consideration.6. Increases in the heart rate induced by orthostatic stress are accompanied by augmentations in the individual variation. More than seasonal difference, individual difference is the major factor responsible for the orthostatic adjustments under thermally neutral environment. Furthermore, the day to day variation within an individual appeared to be the major contributing factor with decreases in the orthostatic tolerance under a hot environment. Less

1.通过阐明荧光和LED光谱对乳头反应的个体差异的影响，我们获得了关于光源对夜间褪黑激素释放影响的适当光谱分布的重要数据.相同光源下墙面的光反射显示，吸收短波成分的木质材料对褪黑素的抑制率低于其他材料.光诱导的褪黑激素抑制率测量生物节律的光敏感性，人类的光敏感机制在冬季响应于不足的日光照明而增强，而高纬度地区的典型的浅色/浅色虹膜适应以增强昼夜节律系统的光敏感性。因此，这些机制的意义在于预防与季节性日照不足相关的抑郁症和相关健康问题。4.生活因素的影响 ...更多信息阐明了基础代谢率降低对耐寒性的影响，即影响耐寒性的因素及其与环境适应相关的生理多态性。根据与生活习惯调查的相关性，制定了提高耐寒力的生活活动指南.在同一室内条件下，以自我冷热敏感视角的主观感受为参照，通过对皮肤温度和核心温度的定量分析以及主观数据的分析，发现在考虑性别、年龄和季节差异的情况下，主观评价未必能从生理反应的角度反映环境适应.立位应激引起的心率增加伴随着个体差异的增大。在热中性环境下，个体差异是影响立位调节的主要因素，而非季节差异。此外，在炎热的环境中，个体内的日变化似乎是立位耐力下降的主要因素。少