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Longitudinal study of the benefit of exercise training for the prevention of age-related decline in activity of daily living and cognitive function

运动训练对预防与年龄相关的日常生活活动能力和认知功能下降的益处的纵向研究

基本信息

批准号：
16300224
负责人：
TOBA Kenji
金额：
$ 8.58万
依托单位：
Kyorin University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2006
项目状态：
已结题

项目摘要

This research was conducted to find a suitable exercise training program to prevent age-related functional decline in older adults. The cohort is members of athletic sports club branched all over Japan : 4,700 people, 16-88 years old (average age 54.8 y/o). We followed physical fitness, independence of ADL, cognitive function, depressive mood, participation in social activities and others. After three years of follow-up period, we obtained following findings. (1) Vitality scale (VS) provides a reliable and valid measure for the QOL of the healthy elderly individuals, and exercise appears beneficial for preventing age-associated decline in VS. (2) Regular exercise for a long period prevents age-associated decline in VS, thereby contributing to care prevention for elderly individuals. (3) Regular exercise in climacteric women gives various benefits, such as decrease in body fat, increase in bone mass, prevention of arteriosclerosis, and balance capability. (4) Appropriate exercise can improve multiple (physical, metabolic, and psychological) functions of healthy elderly individuals. (5) For elderly people who do exercise regularly, past history of fall, tripping, and age are the independent predictors of future falls. 【○!6】 From an animal study, regular exercise prevents atherosclerosis by augmenting antioxidant capacity.Our studies established a useful measure to evaluate the QOL of healthy middle-life and elderly individuals. The vitality scale will give benefit to identify frail people who will possibly enter into care-need status. With this scale, exercise was shown to prevent age-related decline in VS. We were also able to demonstrate various benefits exercise can give, such as anti-arteriosclerotic effect and increase in bone mass. We are still pursuing this cohort, and hope to keep obtaining important data about the effect of exercise.

本研究旨在寻找一种合适的运动训练计划，以预防老年人与年龄相关的功能下降。该队列是遍布日本各地的体育运动俱乐部的成员：4，700人，16-88岁（平均年龄54.8岁）。随访了身体素质、ADL独立性、认知功能、抑郁情绪、社会活动参与等。经过三年的随访，我们获得了以下结果。(1)活力量表（Vitality Scale，VS）为健康老年人的生活质量提供了一个可靠有效的测量方法，运动似乎有利于预防年龄相关的VS下降。（2）长期规律运动可以预防年龄相关的VS下降，从而有助于老年人的护理预防。(3)更年期妇女经常锻炼有各种好处，如减少体内脂肪，增加骨量，预防动脉硬化和平衡能力。(4)适当的运动可以改善健康老年人的多种（身体，代谢和心理）功能。(5)对于经常锻炼的老年人来说，过去的跌倒史、绊倒史和年龄是未来福尔斯的独立预测因素。○！6]动物实验表明，有规律的运动可以通过增强抗氧化能力来预防动脉粥样硬化。我们的研究建立了一个评估健康中老年人生活质量的有用指标。活力量表将有助于确定可能进入护理需要状态的体弱者。有了这个量表，运动被证明可以防止年龄相关的VS下降。我们还能够证明运动可以带来的各种好处，如抗动脉炎作用和骨量增加。我们仍在追踪这一队列，并希望继续获得有关运动效果的重要数据。