Human Sensing Device by Use of Artificiality Synthesized Diamond EQCM

我们在世界上第一次成功地制作了钻石EQCM。硼掺杂的钻石（BDD后） QCM电极是通过使用回流（热处理）方法制造的，EQCM传感器是完全稳定在实验室电化学使用的条件下的，并测试金属沉积、氢和氧进化反应和氧化反应在酸溶液中的氧化反应。作为一种电化学微重力测量工具，我们已确认质量敏感性为48.1赫兹·厘米^2/μg。该项目的最终目标是对BDD表面进行表面修饰，包括各种手性氨酸分子或DNA分子，并对DNA或生物传感器进行应用，第一步是对BDD表面进行碳氧化或氨终止。XPS是用来表征它准备的表面的。因此，准备碳终止或离子终止的BDD EQCM电极已应用于BDD电极，例如， Fe（CN）_<6^<3-/4->，等等，以及BDD和还原特性表面电荷之间的相互作用，在解决方案中被讨论。我们在未来的研究中的目标是制造DNA数字传感器，而不是使用DNA修饰的BDD EQCM电子，没有任何电化学标记器，例如， ferrocene等。

We have succeeded in the fabrication of diamond EQCM for the first time in the world. The boron-doped diamond (hereinafter BDD) QCM electrode was fabricated by use of reflow (heat treatment) method, the EQCM sensor was stabilized completely under laboratory conditions for electrochemical use, and examined for the metal deposition, hydrogen & oxygen evolution reactions and the oxidation reaction of the diamond surface in the acidic solution. As an electrochemical micro gravimetry tool we have confirmed the mass sensitivity was 48.1 Hz・cm^2/μg.The final goal of this project was the surface modification of BDD EQCM with various chiral amono-acid molecules or DNA molecules and their application to DNA or bio-sensor.First step was the carboxylation, or amono-termination of BDD surface. XPS was used for the characterization of thus prepared surface. Thus prepared carboxy-terminated or amono-terminated BDD EQCM electrodes were applied to the exploration of outer sphere electron transfer reaction on BDD electrode, e.g, Fe(CN)_<6^<3-/4->>, etc.And the interaction between surface charge of BDD and redox species in the solution was discussed. Our aim of this study in near future is the fabrication of DNA digital sensor by use of DNA modified BDD EQCM electrode without any electrochemical marker, e.g, ferrocene, etc.