Brain mechanism on the binaural hearing and auditory-visual interaction assessed by the auditory evoked magnetic fields as well as conventional psychophysical methods

1.双耳响度总和：众所周知的双耳响度总和效应是一种心理物理现象，无法通过N100m的测量来验证。虽然响度感觉被认为与听觉神经的总兴奋水平有关，但听觉皮层（如N100m）的总电位可能并不一定反映响度感觉。背景噪声下的信号检测：双耳去掩蔽是指在掩蔽条件下，当一个音调呈现为非相位而非同相位时，可理解性的提高。2 .心理物理双耳揭开可以通过脑磁图（MEG）定量评价正常健康受试者和意识障碍患者双侧半球听觉皮层水平的双耳揭开。时间强度交易：时间强度交易与双耳对声音的定位能力有关，在正常情况下和模拟单侧听力障碍情况下进行观察。单方干扰似乎影响了时间强度交易。视觉输入对听觉诱发磁场N100m的影响：本研究虽然观察到视觉输入对听觉诱发磁场N100m的影响，但基本上没有得到积极的影响。诊断为“功能性听力损失”的儿童听觉功能异常的神经磁证据：功能性听力损失（functional hearing loss， FHL）被定义为没有机体基础的听力障碍。在本研究中，我们检查了基于常规耳科检查诊断的FHL患者的皮质反应。结果提示，部分FHL患者听觉皮层水平存在功能异常，可通过aef客观评价。

1.Binaural loudness summation: The well-known binaural effects of loudness summation, which is observed as a psychophysical phenomenon could not be verified by the N100m measurements. Although the loudness sensation considered to be related to the summed excitation level of auditory nerves, the summed potential from the auditory cortex (as N100m) might not necessarily reflect the loudness sensation.2.Signal detection in background noise : Binaural unmasking refers to the improvement in intelligibility under conditions of masking when a tone is presented out of phase rather than in phase. Psychophysical binaural unmasking can be quantitatively evaluated by magnetoencephalography (MEG) in the auditory cortex level of the bilateral hemispheres in normal healthy subjects as well as in patients with the disturbance of consciousness.3.Time-intensity trading : Time-intensity trading, which is related to the binaural ability to localize the sound, was observed under the normal condition as well as under the simulated condition of unilateral hearing disturbance. The unilateral disturbance appears to affect the time-intensity trading.4.Effect of visual input on the N100m of the auditory evoked magnetic field : Although the effects of visual input on the N100m of the auditory evoked magnetic field was observed in the present study, basically no positive effects could not been obtained.5.Neuromagnetic evidence of abnormal auditory function in children diagnosed as "functional hearing loss" : Functional hearing loss (FHL) is defined as the hearing disturbance for which there is no organic basis. In the present study, the cortical responses in patients with FHL diagnosed based on the conventional otological examinations was examined. The results suggest that some FHL patients have abnormal function at the level of auditory cortex that can be objectively evaluated by AEFs.