Imaging of pain by MRI-About the muscle of mastication in the temporomandibular arthrosis-

MRI疼痛成像-关于颞下颌关节病的咀嚼肌-

基本信息

  • 批准号:
    17591980
  • 负责人:
  • 金额:
    $ 1.84万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    2005
  • 资助国家:
    日本
  • 起止时间:
    2005 至 2007
  • 项目状态:
    已结题

项目摘要

This study examined the pain of the masticatory muscles in the temporomandibular arthrosis with MRI. The imaging sequence imaged it by Magnetization Transfer Contrast (MTC) method and examined Magnetization Transfer Ratio (MTR) than a provided image.1. As a result of I photographed 2%, 4%, 6%, 8%, agar of 10% by the fundamental experiment that I used agar for, and having measured MTR, as 10% agar was expensive, and quantity of water increased, it lowered, and 2% agar was low most. MTR was controlled by moisture content, and it was suggested that it lowered so that moisture content increased.2. I intended for a volunteer and the temporomandibular arthrosis patient who appealed to a masseter muscle of one side for pain and examined Magnetization Transfer Ratio (MTR). I recognized the difference that was shifts and changes to a difference of the pain side and the non-pain side of laterality of masseter muscle MTR in a volunteer and masseter muscle MTR in a temporomandibular arthrosis patient. MTR reflected histopathology of a sharp pain side masseter muscle, and it was suggested that I was useful in image inspection of a masseter.When I was influenced by moisture content, and MTR changed than the fundamental experiment that I used agar for, and moisture content increased, MTR decreased. Masseter muscle MTR of the pain side of the temporomandibular arthrosis patient showed a low tendency in comparison with the non-sharp pain side. The existence of the morbid change to let free water in the pain side masseter muscle organization increase as for this was suggested. In other words it seemed that the existence of the lesion such as the edema that I cannot depict was thought about in T2WI, and the lesion might be connected with the appearance of the pain.
这项研究通过 MRI 检查了颞下颌关节中咀嚼肌的疼痛。成像序列通过磁化传递对比(MTC)方法对其进行成像,并检查与提供的图像相比的磁化传递比(MTR)。 1.在使用琼脂的基本实验中拍摄了2%、4%、6%、8%、10%的琼脂,测定了MTR,结果10%琼脂价格昂贵,并且水量增加而降低,2%琼脂最低。 MTR受含水量控制,建议含水量增加则降低MTR。 2.我的对象是一位志愿者和一位颞下颌关节病患者,他们通过一侧的咬肌来缓解疼痛,并检查了磁化传递比(MTR)。我认识到志愿者咬肌 MTR 偏侧性和颞下颌关节病患者咬肌 MTR 疼痛侧和非疼痛侧差异的变化和变化。 MTR反映了剧烈疼痛的侧咬肌的组织病理学,这表明我对咬肌的图像检查很有用。当我受到水分含量的影响时,MTR比我使用琼脂进行的基本实验发生变化,并且水分含量增加,MTR减少。颞下颌关节病患者的疼痛侧咬肌MTR与非锐痛侧相比表现出较低的趋势。对此提出了让疼痛侧咬肌组织中的游离水增加的病态变化的存在。也就是说,T2WI似乎考虑到了我无法描绘的水肿等病变的存在,并且该病变可能与疼痛的出现有关。

项目成果

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The elucidation of the pathogenic mechanism and the transition of pathological condition at the bone and cartilage destruction of IL-17 in temporomandibular arthrosis.
阐明IL-17在颞下颌关节病中骨、软骨破坏的发病机制及病理状态转变。
  • 批准号:
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  • 财政年份:
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阐明发病机制和颞下颌关节病患者的变化,建立软骨破坏的观察点
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  • 财政年份:
    2007
  • 资助金额:
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  • 项目类别:
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