The basic research for the association of exercise and fitness with mental health status

运动健身与心理健康状况关联的基础研究

• 批准号: 18500548
• 负责人: NAGANO Mayumi
• 金额: $ 2.63万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18500548/
• 关键词: mental health; cardiorespiratory fitness; elderly people; diabetes mellitus; fatty liver; hepatic enzyme; 運動; 体力; メタボリックシンドローム

The present study was performed according to following themes;Theme 1: Selection of questionnaire for the present studyWe examined the coordination between an answer to each questionnaire and physiological and biochemical indices, and decided to adopt the General Health Questionnaire (GHQ) for the present study.Theme 2: The association between objective fitness and mental health in elderly people in a community.In the elderly people in a community, no significant association was recognized between objective fitness and mental health.Theme 3: The association among cardiorespiratory fitness, pathology and mental health in newly diagnosed diabetic patients. Sub theme 1) The impact of cardiorespiratory fitness on prevalence of metabolic abnormalityIt was suggested that low cardiorespiratory fitness was strongly associated with elevated aspartate- aminotransferase (AST) and alanine-aminotransferase (ALT) which were the indices of hepatic function. No report has so far reported such phenomen … More a, it was therefore needed the following study to clarify its mechanism.Sub theme 2) The investigation for the association among mental health, cardiorespitratory fitness and fatty liver and hepatic enzymesIn the patients having fatty liver, cardiorespiratory fitness and hepatic enzyme level were significantly worsened in the group with aggravated mental health than that in the group with normal mental health. In addition, the aggravated mental health was associated with low cardiorespiratory fitness after adjusting for visceral fat area and the other metabolic abnormalities. It was therefore suggested to be one of pathways that aggravated mental health might suppressed exercise behavior, and followed by high prevalence of metabolic abnormalities.In summary, it was suggested that mental health was associated with cardiorespiratory fitness and metabolic markers in the diabetic patients rather than the healthy elderly people. In addition, the hepatic enzyme level could be able to be one of new biomarkers to express mental health status. Less

本研究围绕以下主题展开：主题1：调查问卷的选择我们考察了每个问卷的答案与生理生化指标的协调性，并决定采用一般健康问卷(GHQ)进行研究。主题2：社区老年人目标健康与心理健康的关系。在社区老年人中，目标健康与心理健康之间没有显著的关联。主题3：新诊断的糖尿病患者心肺功能、病理和心理健康之间的关系。副主题1)心肺适能对代谢异常患病率的影响提示心肺适能低下与天冬氨酸转氨酶(AST)和丙氨酸氨基转移酶(ALT)升高密切相关，而天冬氨酸转氨酶和丙氨酸转氨酶是肝功能的指标。到目前为止，还没有报道过这种现象的…2)心理健康、心肺功能与脂肪肝和肝酶关系的研究在脂肪肝患者中，心理健康加重组的心肺功能和肝酶水平明显低于心理健康正常组。此外，在调整内脏脂肪面积和其他代谢异常后，心理健康状况的恶化与心肺功能低下有关。因此，这可能是心理健康恶化可能抑制运动行为的途径之一，并伴随着代谢异常的高患病率。综上所述，糖尿病患者的心理健康与心肺功能和代谢标志物有关，而不是健康老年人。此外，肝酶水平有望成为反映心理健康状况的新的生物标志物之一。较少

项目成果

医学書院

医学书院

• 发表时间: 2015
• 期刊: 臨床外科
• 作者: Isomoto H;Nanashima A;Senoo T;Ogiwara K;Hashisako M;Ohnita K;Yamaguchi N;Kunizaki M;Hidaka S;Fukuda H;Ishii H;Matsushima K;Minami H;Akazawa Y;Takeshima F;Fukuoka J;Nagayasu T;Nakao K.;村上豪志
• 通讯作者: 村上豪志

Cardiorespiratory fitness was associated with psychological distress in patients with glucose intolerance and fatty liver.

心肺健康与葡萄糖耐受不良和脂肪肝患者的心理困扰相关。

• 发表时间: 2007
• 作者: 和田 佳郎;竹村 文;河野 憲二;Nagano M
• 通讯作者: Nagano M

Textbook for health and exercise epidemiology. (Section 2, Exercise epidemiology of metabolic syndrome, written by Nagano ; Exercise epidemiology of mental health, written by Kumagai)

健康和运动流行病学教科书。

• 作者: Nagano;M.;Kumagai;S
• 通讯作者: S

第2章:健康と運動の疫学・各論.(2)肥満・メタボリックシンドロームの運動疫学

第二章：健康与运动的流行病学和细节（2）肥胖和代谢综合征的运动流行病学。

• 发表时间: 2008
• 作者: 熊谷 秋三;田中 喜代次;藤井 宣晴編
• 通讯作者: 藤井 宣晴編

健康と運動の疫学入門(関連部分 : 第2章,肥満・メタボリックシンドロームの運動疫学,メンタルヘルスの運動疫学)

健康与运动流行病学简介（相关部分：第二章，肥胖与代谢综合征的运动流行病学，心理健康的运动流行病学）

• 发表时间: 2007
• 作者: 熊谷秋三ら編著;長野真弓(分担執筆者)
• 通讯作者: 長野真弓(分担執筆者)