Predicting the tumor response to radiotherapy for high-grade gliomas: Clinical significance of hypoxia-related genes
Predicting the tumor response to radiotherapy for high-grade gliomas: Clinical significance of hypoxia-related genes
批准号:
18591386
负责人:
OGAWA Kazuhiko
金额:
$2.5万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2007
中文摘要
1)高级别胶质瘤的治疗方案已经建立。2)分析了肿瘤细胞和基质敏感性的影响,发现肿瘤细胞和基质敏感性都影响肿瘤对放射的反应。3)根据方案收集了高级别胶质瘤的临床标本。4)我们正在研究低氧相关基因与高级别胶质瘤放射反应的关系。等级胶质瘤。
英文摘要
1) Treatment protocol for high-grade gliomas has been established.2) Influence of tumor cell and stroma sensitivy has been analyzed and both tumor cell and storma sensitivity were found to have influence on tumor response to radiation.3) Clinical samples of high grade gliomas have been collected according to the protocol.4) We are now investigating the relation between the hypoxia-related genes and tumor response to radiotherapy for high-grade gliomas.
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Hyperfractionated radiotherapy and multi-agent chemotherapy (procarbazine, ACNU and vincristine) for high-grade gliomas : a prospective study
高级别胶质瘤的超分割放疗和多药化疗(丙卡巴肼、ACNU 和长春新碱):一项前瞻性研究
DOI:
--
发表时间:
2006
期刊:
Anticancer Research 26
影响因子:
--
作者:
[Ogawa K, Yoshii Y, Tsuchida Y Murayama S, et al.]
通讯作者:
et al.
DOI:
10.1158/0008-5472.can-06-4498
发表时间:
2007-05-01
期刊:
CANCER RESEARCH
影响因子:
11.2
作者:
[Ogawa, Kazuhiko, Boucher, Yves, Gerweck, Leo E.]
通讯作者:
Gerweck, Leo E.
DOI:
10.1158/0008-5472.can-06-0533
发表时间:
2006-09-01
期刊:
CANCER RESEARCH
影响因子:
11.2
作者:
[Gerweck, Leo E., Vijayappa, Shashirekha, Chen, David J.]
通讯作者:
Chen, David J.
腫瘍細胞及び間質の放射線感受陛における放射線治療効果に対する影響
肿瘤细胞和间质的放射敏感性对放射治疗效果的影响
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[小川和彦, 村山貞之, 他]
通讯作者:
他
悪性グリオーマに対する放射線照射とHBOの併用療法
放射线照射与HBO联合治疗恶性胶质瘤
DOI:
--
发表时间:
2006
期刊:
影响因子:
--
作者:
[小川和彦, 吉井與志彦, 土田幸広, 村山貞之, 他]
通讯作者:
他
共 10 条
Significance of hypoxia-related genes to predict the tumor response to radiotherapy in patients with oropharyngeal cancer
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批准号:21591615
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
-
财政年份:2009
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负责人:OGAWA Kazuhiko
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依托单位:
海外基金