Protective effect on stress-related memory deficits by chewing
Protective effect on stress-related memory deficits by chewing
批准号:
19390493
负责人:
WATANABE Kazuko
金额:
$9.82万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
一开始就提出了一种可以在少量血液和短时间内测量出应激指标的新方法。轻度抑制应激包括白细胞数量轻度减少和纤维蛋白凝血时间缩短,但变异性较大,小鼠需要全血量,适合行为学分析。在morris水迷宫实验中,轻度抑制应激诱导小鼠自发咀嚼行为,增强小鼠学习效果。
英文摘要
A new method for measuring method of stress indicator, which is measurable in a slightamount of blood andshort time, had been developed at the beginning. Mild restrain stress induded a alight decrease of leucocyte number and shortening fibrin clotting time , but variability was quite-variable and whole volume of blood was necessary in mice, which is suitable for behavioral analysis. Spontaneous chewing behavior was induced during mild restrain stress and enhanced learning effect in the morris water maze test.
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Changes in GFAP-immunoreactive astrocytes induced by the bite-raised condition in aged SAMP8 mice.
老年 SAMP8 小鼠咬伤引起的 GFAP 免疫反应性星形胶质细胞的变化。
DOI:
--
发表时间:
2008
期刊:
Biogenic Amines 22
影响因子:
--
作者:
[Y. Ichihashi, Y. Arakawa, M. Iinuma, Y. Tamura, K. Kubo, F. Iwaku, T. Takahashi, N. Karasawa, I. Nagatsu, M. Onozuka]
通讯作者:
M. Onozuka
Chewing ameliorates stress- suppressed hippcampal CA1-LTP via activation of histamine H1 receptor
咀嚼通过激活组胺 H1 受体改善压力抑制的海马 CA1-LTP
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Ono Y, Kataoka T, Miyake S, Sasaguri KI, Sato S, Onozuka M]
通讯作者:
Onozuka M
Bruxisum affects stress responses in stressed rats.
磨牙会影响应激大鼠的应激反应。
DOI:
--
发表时间:
2010
期刊:
Clin Oral Investig 14
影响因子:
--
作者:
[Sato C, Sato S, Takashina H, IshiiH, Onozuka M, Sasaguri K.]
通讯作者:
Sasaguri K.
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kubo KY, Sasaguri K, et al]
通讯作者:
et al
Interactions between chewing and brain activity in humans, In Nover Trends in Brain science
人类咀嚼与大脑活动之间的相互作用,《诺弗脑科学趋势》
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Onozuka M, Hirano Y, Tachibana A, Kim W, Ono Y, Sasaguri K, Kubo K, Niwa M, Kanematsu K, Watanabe K]
通讯作者:
Watanabe K
共 22 条
Chewing effects on intelligent activities in the elderly
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批准号:15390590
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.41万
-
财政年份:2003
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负责人:WATANABE Kazuko
-
依托单位:
Molecular Cloning of a Novel Type of Glutamate Receptor Eliciting Membrane Hyperpolarization in a Single Cell Level.
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批准号:09680762
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.7万
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财政年份:1997
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负责人:WATANABE Kazuko
-
依托单位:
海外基金