The study on regeneration of dental enamel using synthetic phosphorylated polypeptides

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Phosphorylated polypeptides (protein) has been successful in chemical synthesis in our laboratory. Also, the synthetic phosphorylated polypeptides were adsorbed on the surface of tooth enamel, and then the hydroxyapatite (hard tissues of teeth, bone etc.) was made by deposition of calcium. These results were suggested a possibility for tooth cavity restoration or pit and fissure modification of teeth (sealant) as a new dental treatment method, making a great deal of contribution to the dental profession.