An artificial placenta using a sheep model

我们的目的是开发一种无泵动静脉体外生命支持回路形式的人工胎盘，其中婴儿自身的血压驱动该系统。在动物实验中，我们可以证明，该系统可以支持气体交换和维持胎儿循环15~30小时。长时间支持确保脑氧输送需要基于低阻力氧合器的并联回路。

Our purpose was to develop an artificial placenta in a form of a pumpless arteriovenous extracorporeal life support circuit, in which infant's own blood pressure droved the system. In an animal experiment using the chronically instrumented fetal sheep, we could demonstrate that this system could support gas exchange and maintain fetal circulation for 15~30 hours. Prolonged support assured cerebral oxygen delivery would require a parallel circuit based on a low resistance oxygenator.