Circular-dichroism stopped-flow spectrometer for rapid molecular interactions and membrane transport.

用于快速分子相互作用和膜传输的圆二色性停流光谱仪。

• 批准号: LE0347746
• 负责人: Em/Prof Stephen Tyerman
• 金额: $ 13.58万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2003-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0347746
• 关键词: Circular; dichroism; stopped; flow; spectrometer

A stopped-flow spectroscope is requested that can capture the rapid kinetics of changes in conformation of biopolymers, macromolecules and chiral catalysts as they interact with other molecules. This includes measurement of rapid transport of solutes through membrane proteins in lipid membranes. The versatile instrument can also determine circular dichroism spectra of peptides, proteins, tannins, pigment complexes and chiral catalysts that is required within several existing collaborations to understand the tertiary structures, stability and interactions between the complex molecules. The instrument will significantly strengthen research on macromolecules and polymers that have applications in the wine industry, nanotechnology, and biotechnology.

要求停流光谱仪能够捕获生物聚合物、大分子和手性催化剂在与其他分子相互作用时构象变化的快速动力学。这包括测量溶质通过脂质膜中的膜蛋白的快速转运。多功能仪器还可以确定肽，蛋白质，单宁，色素复合物和手性催化剂的圆二色光谱，这是在几个现有的合作中所需的，以了解复杂分子之间的三级结构，稳定性和相互作用。该仪器将大大加强对葡萄酒工业、纳米技术和生物技术中应用的大分子和聚合物的研究。