Construction of hybrid supramolecular capsule through hydrogen bond and metal-ligand coordination bond, and dynamic guest encapsulation

以四溴空化体为原料，经6步合成了多功能化C_<2v>-空化体。合成的空腔体与Pt(dppp)(OTf)_2在CDCl_3或CD_2Cl_2中以1:1的比例混合，通过氢键和金属配位键定量自组装成超分子杂化胶囊。胶囊腔内充满三氟酸盐离子和渗透的脲基。该胶囊在阴离子的帮助下包裹中性客体分子，如4,4 '-二碘多联苯。包封配合物经核磁共振技术鉴定。客体交换的动力学是由阴离子的数量和/或类型或其他影响因素如溶剂的极性控制的。

Multifunctionalized C_<2v>-cavitand was synthesized in six steps from a tetrabromo cavitand. A 1:1 mixture of the synthesized cavitand and Pt(dppp)(OTf)_2 in CDCl_3 or CD_2Cl_2 quantitatively self-assemble into a supramolecular hybrid capsule through hydrogen bond and metal-ligand coordination bond. Cavity of the capsule is filled with triflate ion and penetrated alkyl groups of ureides. The capsule encapsulates a neutral guest molecule such as 4, 4'-diiodobiphenyl with the assistance of an anion. Encapsulation complex was identified by NMR technic. The kinetics of guest exchange is controllable by the amounts and/or types of anions or other influences such as the polarity of the solvent.