Micro-simulation for inhaled particle tracking using image-based model human airways

在基于x射线CT图像构建的人体气道三维真实模型中，对振荡流中粒子的跟踪进行了计算流体动力学（CFD）模拟。颗粒跟踪表明，在分叉处流动分离的方向依赖的速度分布促进了气道内轴向流体的分散。在小气道扩张和收缩模型中，颗粒的方差随体积变化的增加而增加。

Computational fluid dynamics (CFD) simulations were carried out for particle tracking in oscillatory flow in a 3D realistic model of the human airways constructed based on X-ray CT images. Particle tracking revealed that the direction-dependent velocity profile with flow separation at the bifurcation promotes axial fluid dispersion in the airways. It was also found that the variance of the particles increases with the increase of volume change in an expanding and contracting model of small airways.