The anesthetic modulation of the protective effect of statin on the endothelium function in diabetic and hypertensive animal models.
The anesthetic modulation of the protective effect of statin on the endothelium function in diabetic and hypertensive animal models.
批准号:
19591815
负责人:
OGAWA Koji
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
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英文摘要
Exposure of cultured endothelial cells to simvastatin induced NO production. The increase in NO production was significantly inhibited in the presence of sevoflurane. Sevoflurane also inhibited increase in eNOS expression in response to simvastatin, but not eNOSmRNA expression. It is suggested the transcriptional modification of eNOS may be involved in the statin-induced activation of eNOSNO signaling pathways. Sevoflurane appears to affect this process.
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Acute effect of simvastatin on nitric oxide synthesis in bovine aortic endothelial cells.
辛伐他汀对牛主动脉内皮细胞一氧化氮合成的急性影响。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Tange K, Tokinaga Y, Ogawa K, Kuriyama T, Hatano Y]
通讯作者:
Hatano Y
Vasopressin restores the hyporesponsiveness of vascular smooth muscle to norepinephrinee in sepsis.
加压素可恢复败血症时血管平滑肌对去甲肾上腺素的低反应性。
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Yamazaki A, Tokinaga Y, Iranami H, Ogawa K, Hatano Y]
通讯作者:
Hatano Y
Simvastatin restores the impaired endothelium-dependent relaxation in diabetic rats
辛伐他汀恢复糖尿病大鼠受损的内皮依赖性舒张
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Sugimoto K, Ogawa K, Tokinaga Y, Tange K, Hatano Y]
通讯作者:
Hatano Y
ウシ大動脈内皮細胞における一酸化窒素 (NO) 産生量に対するシンバスタチンの急性効果
辛伐他汀对牛主动脉内皮细胞一氧化氮(NO)产生的急性影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[丹下和晃, 時永泰行, 井上真理子, 佐古有希子, 小川幸志, 畑埜義雄]
通讯作者:
畑埜義雄
急性シンバスタチン投与による一酸化窒素合成酵素発現に及ぼすセボフルランの影響
七氟醚对辛伐他汀急性给药诱导的一氧化氮合酶表达的影响
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[丹下和晃, 時永泰行, 谷奥匡, 平井亜葵, 小川幸志, 畑埜義雄]
通讯作者:
畑埜義雄
共 24 条
Deformation-controlling design of steel frames under strong earthquakes
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批准号:24560689
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.49万
-
财政年份:2012
-
负责人:OGAWA Koji
-
依托单位:
OPTIMUM STRENGTH DISTRIBUTION OF STRUCTURAL MEMBERS IN MULTI-STORY STEEL FRAMES
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批准号:21560594
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2009
-
负责人:OGAWA Koji
-
依托单位:
Earthquake Response of Steel Frames Subjected to Horizontal Bi-directional Ground Motions
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批准号:19560576
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2007
-
负责人:OGAWA Koji
-
依托单位:
Fundamental Study on Seismic Response of Steel Moment Frames Sustaining Beam-Hinging Mechanism
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批准号:17560512
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2005
-
负责人:OGAWA Koji
-
依托单位:
Plastic Deformation of Beams in Steel Moment Frames Subjected to Strong Earthquakes
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批准号:15560495
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:2003
-
负责人:OGAWA Koji
-
依托单位:
Performance-based Design of Steel Moment Frames Sustaining Beam-Hinging Mechanism
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批准号:13650632
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.43万
-
财政年份:2001
-
负责人:OGAWA Koji
-
依托单位:
EFFECTS OF GENERAL ANESTHETICS ON INTRACELLULAR CALCIUM CONCENTRATION AND NITRIC OXIDE PRODUCTION OF VASCULAR ENDOTHELIUM
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批准号:13671607
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.6万
-
财政年份:2001
-
负责人:OGAWA Koji
-
依托单位:
Capacity Requreiment of Steel Moment Frames in Compliance with Seismic Demand
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批准号:11650590
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1999
-
负责人:OGAWA Koji
-
依托单位:
STUDY ON SEISMIC DESIGN CRITERIA FOR STEEL FRAMES CONSIDERING DEGRADING LOAD-DEFLECTION CURVES
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批准号:06650639
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1994
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负责人:OGAWA Koji
-
依托单位:
The synthesis of carbon 11 labeled pharmaceuticals for PET by malonic ester synthesis and related methods
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批准号:05671903
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
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财政年份:1993
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负责人:OGAWA Koji
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依托单位:
海外基金