Mechanism of Ionizing Radiation Induced Modulation of the Salt Chemotaxis Learning in C. elegans

我们开发了一种新的NaCl浓度范围为1 ~ 100 mM的趋化性群体测定系统，发现odr-3基因负责电离辐射诱导的盐趋化性学习的调节。此外，我们利用神经网络分析估计了与盐趋化性学习相关的神经传递。此外，我们开始检测没有氧化应激反应基因的突变体。

We developed a new chemotaxis population assay system with a broad NaCl concentration range from 1 to 100 mM. Using this assay system, we found that odr-3 gene was responsible for ionizing radiation induced modulation of the salt chemotaxis learning. In addition, we estimated the neurotransmission related to the salt chemotaxis learning using the neural network analysis. Moreover, we started the examination for mutants without oxidative stress response genes.