Asymmetric Catalytic Synthesis of Optically Active Organoboron Compounds with Chiral Borylcopper Species

点击翻译按钮获取中文摘要

Novel methods for efficient synthesis of optically active organoboron compounds with chiral copper(I)-catalyst have been developed. The reactions, which include copper(I) salts and chiral phosphine ligands, promote various borylation reaction to produce optically active organoboron compounds with high enantioselectivity. This method enables the asymmetric catalytic synthesis of unprecedented chiral cyclopropyl-, ally- and homoallyboronates, which will facilitate the synthesis of intermediates for medicines.