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Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases

Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases
新型 NADPH 氧化酶亚型在生活方式相关疾病发生中的作用研究
批准号:
20390071
负责人:
YABE Chihiro
金额:
$12.98万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

项目摘要

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YABE Chihiro的其他基金

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中文摘要
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英文摘要
Induction of hyperglycemia with streptozotocin up-regulated the expression of NOX1, a novel isoform of superoxide-generating NADPH oxidase in the kidney. NOX1 derived ROS were shown to increase oxidative stress and to activate p38 MAPK, thereby stimulating renal redox-sensitive signaling under diabetic conditions.
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会议论文
Renal redox-sensitive signaling in type 1 diabetes is suppressed in Nox1-deficient mice.
Nox1 缺陷小鼠中 1 型糖尿病中的肾脏氧化还原敏感信号传导受到抑制。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Zhu K, Matsumoto M, Iwata K, Yabe-Nishimura C.]
通讯作者: Yabe-Nishimura C.
DOI: 10.1016/j.bbrc.2008.07.027
发表时间: 2008-09-19
期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子: 3.1
作者: [Cevik, Muhammer Ozgur, Katsuyama, Masato, Yabe-Nishimura, Chihiro]
通讯作者: Yabe-Nishimura, Chihiro
糖尿病性腎症モデルにおける活性酸素産生酵素Nox1の解析
糖尿病肾病模型中活性氧产生酶Nox1的分析
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [筧朋子, 岩田和実, Taye Ashraf, 松野邦晴, 矢部千尋]
通讯作者: 矢部千尋
A study on the role of NOX1/NADPH oxidase in cardiac arrhythmia
  • 批准号:
    23659140
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.41万
  • 财政年份:
    2011
  • 负责人:
    YABE Chihiro
  • 依托单位:
Vascular remodeling in Nox1/NADPH oxidase deficient mice
  • 批准号:
    17590225
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.3万
  • 财政年份:
    2005
  • 负责人:
    YABE Chihiro
  • 依托单位:
Paradoxical roles of the aldehyde-metabolizing enzyme, aldose reductase in cardioprotection
  • 批准号:
    15590470
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.3万
  • 财政年份:
    2003
  • 负责人:
    YABE Chihiro
  • 依托单位: