课题基金 / 基金详情

Regulation of the maturation of cerebellar synapses by PKN

Regulation of the maturation of cerebellar synapses by PKN
PKN 对小脑突触成熟的调节
批准号:
20500354
负责人:
YASUDA Hiroki
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

项目摘要

项目成果

YASUDA Hiroki的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
I investigated the role of PKN1 in synaptic transmission and synaptic plasticity in the central nervous system electrophysiologically using PKN1a knockout (KO) mice. I found LTD was enhanced and heterosynaptic LTD was induced in the hippocampus of developing PKN1a KO mice and synaptic transmission was more immature. I concluded that PKN1 is promoting synaptic maturation by inhibiting LTD during development.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1523/jneurosci.0899-08.2008
发表时间: 2008-07-09
期刊: JOURNAL OF NEUROSCIENCE
影响因子: 5.3
作者: [Huang, Yan, Yasuda, Hiroki, Tsumoto, Tadaharu]
通讯作者: Tsumoto, Tadaharu
Neuron-specific drebrin isoform is necessary for hippocampus-dependent learning in adulthood but not in young age of mice
神经元特异性的drebrin亚型对于成年期海马依赖性学习是必需的,但对于小鼠的年轻期则不然
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Hirano Y, Ishiguro N, Sokabe M, Takigawa M, Naruse K, Kojima N]
通讯作者: Kojima N
Regulation of excitability and plasticity by endocannabinoids and PKA in developing hippocampus
内源性大麻素和 PKA 对发育中海马的兴奋性和可塑性的调节
DOI: --
发表时间: 2008
期刊: Proc Natl Acad Sci (USA)
影响因子: --
作者: [安田浩樹, Yan Huang, Tadaharu Tsumoto]
通讯作者: Tadaharu Tsumoto
DOI: 10.1016/j.neulet.2009.12.078
发表时间: 2010-02
期刊: Neuroscience Letters
影响因子: 2.5
作者: [Yuma Sonoda;H. Mukai;K. Matsuo;Mikiko Takahashi;Y. Ono;K. Maeda;H. Akiyama;T. Kawamata]
通讯作者: Yuma Sonoda;H. Mukai;K. Matsuo;Mikiko Takahashi;Y. Ono;K. Maeda;H. Akiyama;T. Kawamata
PKN1 regulates metaplasticity in hippocampus
  • 批准号:
    23500461
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.33万
  • 财政年份:
    2011
  • 负责人:
    YASUDA Hiroki
  • 依托单位:
Analysis of the mechanisms of the synapse formation of newborn neurons by developing mice with channelrhodopsin-2 only in newborn neuron in the dentate gyrus.
  • 批准号:
    21200016
  • 项目类别:
    Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
  • 资助金额:
    $19.8万
  • 财政年份:
    2009
  • 负责人:
    YASUDA Hiroki
  • 依托单位:
海外基金