Nanobioprobes for Multimodal Imaging Diagnostics of Cancer in Experimental Animals

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The purpose of these experiments is to clarify whether this probe is appropriate for early diagnostics of colon cancer using combined fluorescence/MR imaging. We applied two multimodal quantum dot probes (QD-probe) for cancer imaging in experimental animals, using fluorescent imaging and magnetic resonance imaging. QD-probe (conjugated with PEG and B72.3 using carbodiimide) was injected into the tail vain of the mouse. 7T-MRI and optical imaging allows visualization of the tumor in the early stage. Our research has been reported as manuscripts in peer-reviewed journals and presentations on scientific conferences.