Exercise therapy and immune function in patients with chronic respiratory failure

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The objective was to determine the effects of exercise training on changes in salivary and exhaled breath condensate (EBC) immune function in patients with chronic respiratory disease. As an indicator of an immune functions, secretary immunoglobulin A (SIgA) in saliva and EBC was measured. Airway production of SIgA was unable to be measured in EBC specimens and, therefore, EBC specimens cannot be used to monitor SIgA concentration. Hospital-based pulmonary rehabilitation program which designed exercise training and breathing retraining, did not decrease SIgA and immunity with antioxidants in saliva. The result of this study suggests that pulmonary rehabilitation could be a useful for improving immune function, also makes improving physical conditioning and exercise performance.