Objective study of the influence of visual stimuli to the wakefulness maintenance state against sleepiness by using multi-channel bio-signal processing

我们测量了多通道生物信号，即脑电图、心率变异性、血压、眼动和瞳孔直径变异性，以评估视觉刺激对清醒维持状态对嗜睡的影响。我们对这些信号进行了时频分析、常规频谱分析和反馈建模。结果表明，清醒维持状态下的生理活动与自然睡眠开始时的生理活动具有不同的特征。此外，我们还在脑电图分析中引入了新的伪影去除方法。

We have measured multi-channel bio-signals, i. e., electroencephalogram, heart rate variability, blood pressure, eye movement and pupil diameter variability in order to evaluate the influence of visual stimuli to the wakefulness maintenance state against sleepiness. We performed time-frequency analysis, conventional spectral analysis, and feedback modeling to those signals. All results showed that physiological activities in wakefulness maintenance state have different features from those in onset of natural sleep. In addition, we have introduced new artifact removal methods to the EEG analysis.